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Ryan J Marcheschi

Explore the profile of Ryan J Marcheschi including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 167
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Recent Articles
1.
Gronenberg L, Marcheschi R, Liao J
Curr Opin Chem Biol . 2013 Apr; 17(3):462-71. PMID: 23623045
Next-generation biofuels must be compatible with current transportation infrastructure and be derived from environmentally sustainable resources that do not compete with food crops. Many bacterial species have unique properties advantageous...
2.
Marcheschi R, Gronenberg L, Liao J
Biotechnol J . 2013 Apr; 8(5):545-55. PMID: 23589443
Protein engineering in the context of metabolic engineering is increasingly important to the field of industrial biotechnology. As the demand for biologically produced food, fuels, chemicals, food additives, and pharmaceuticals...
3.
Marcheschi R, Li H, Zhang K, Noey E, Kim S, Chaubey A, et al.
ACS Chem Biol . 2012 Jan; 7(4):689-97. PMID: 22242720
Nature uses four methods of carbon chain elongation for the production of 2-ketoacids, fatty acids, polyketides, and isoprenoids. Using a combination of quantum mechanical (QM) modeling, protein-substrate modeling, and protein...
4.
Marcheschi R, Tonelli M, Kumar A, Butcher S
ACS Chem Biol . 2011 Jun; 6(8):857-64. PMID: 21648432
Programmed -1 translational frameshifting is an essential event in the replication cycle of HIV. Frameshifting is required for expression of the viral Pol proteins, and drug-like molecules that target this...
5.
Marcheschi R, Mouzakis K, Butcher S
ACS Chem Biol . 2009 Aug; 4(10):844-54. PMID: 19673541
HIV-1 requires a -1 translational frameshift to properly synthesize the viral enzymes required for replication. The frameshift mechanism is dependent upon two RNA elements, a seven-nucleotide slippery sequence (UUUUUUA) and...
6.
Marcheschi R, Staple D, Butcher S
J Mol Biol . 2007 Sep; 373(3):652-63. PMID: 17868691
Simian immunodeficiency virus (SIV), like its human homologues (HIV-1, HIV-2), requires a -1 translational frameshift event to properly synthesize all of the proteins required for viral replication. The frameshift mechanism...