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Ryan Bernhisel

Explore the profile of Ryan Bernhisel including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 306
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Recent Articles
1.
Daly M, Rosenthal E, Cummings S, Bernhisel R, Kidd J, Hughes E, et al.
Breast Cancer Res Treat . 2023 Apr; 199(3):617-626. PMID: 37084156
Purpose: Young age at breast cancer (BC) diagnosis and family history of BC are strongly associated with high prevalence of pathogenic variants (PVs) in BRCA1 and BRCA2 genes. There is...
2.
Hughes E, Wagner S, Pruss D, Bernhisel R, Probst B, Abkevich V, et al.
JCO Precis Oncol . 2022 Nov; 6:e2200084. PMID: 36331239
Purpose: Polygenic risk scores (PRSs) for breast cancer (BC) risk stratification have been developed primarily in women of European ancestry. Their application to women of non-European ancestry has lagged because...
3.
Constantinidou A, Marcou Y, Toss M, Simmons T, Bernhisel R, Hughes E, et al.
Clin Cancer Res . 2022 Aug; 28(20):4435-4443. PMID: 36043530
Purpose: The EndoPredict prognostic assay is validated to predict distant recurrence and response to chemotherapy primarily in post-menopausal women with estrogen receptor-positive (ER+), HER2- breast cancer. This study evaluated the...
4.
Stoll J, Rosenthal E, Cummings S, Willmott J, Bernhisel R, Kupfer S
JCO Precis Oncol . 2022 Jan; 4:51-60. PMID: 35050728
Purpose: Prior estimates of breast cancer risk in women with Lynch syndrome (LS) range from population risk to 18-fold increased risk with reported differences by gene. Here, breast cancer rates...
5.
Kurian A, Hughes E, Simmons T, Bernhisel R, Probst B, Meek S, et al.
Cancer . 2021 Jul; 127(20):3742-3750. PMID: 34228814
Background: The IBIS/Tyrer-Cuzick model is used clinically to guide breast cancer screening and prevention, but was developed primarily in non-Hispanic White women. Little is known about its long-term performance in...
6.
Cummings S, Roman S, Saam J, Bernhisel R, Brown K, Lancaster J, et al.
J Ovarian Res . 2021 Apr; 14(1):61. PMID: 33926482
Background: Professional society guidelines recommend risk-reducing salpingo-oophorectomy (RRSO) for women with pathogenic variants (PVs) in ovarian cancer-risk genes. Personalization of that intervention is based on gene-specific phenotypes; however, the age...
7.
Weitzel J, Kidd J, Bernhisel R, Shehayeb S, Frankel P, Blazer K, et al.
Breast Cancer Res Treat . 2021 Apr; 188(3):759-768. PMID: 33826040
Purpose: The prevalence, penetrance, and spectrum of pathogenic variants that predispose women to two or more breast cancers is largely unknown. Methods: We queried clinical and genetic data from women...
8.
Hall M, Bernhisel R, Hughes E, Larson K, Rosenthal E, Singh N, et al.
Cancer Prev Res (Phila) . 2021 Jan; 14(4):433-440. PMID: 33509806
Pathogenic variants (PVs) in are relatively common, but the scope and magnitude of risk remains uncertain. This study aimed to estimate PV cancer risks independent of family cancer history. This...
9.
Calip G, Kidd J, Bernhisel R, Cox H, Saam J, Rauscher G, et al.
Breast Cancer Res Treat . 2020 Sep; 185(1):195-204. PMID: 32918117
Purpose: The role of genetic predisposition in male breast cancer (MBC) patients who test negative for a BRCA mutation is unclear. The aim of this study is to define the...
10.
Kurian A, Bernhisel R, Stefanick M
JAMA . 2020 Jul; 324(4):397-398. PMID: 32721001
No abstract available.