Ruichen Rong
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Explore the profile of Ruichen Rong including associated specialties, affiliations and a list of published articles.
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30
Citations
963
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Recent Articles
11.
Luo D, Robertson S, Zhan Y, Rong R, Wang S, Jiang X, et al.
bioRxiv
. 2023 Aug;
PMID: 37546786
Motivation: Spatial transcriptomics (ST) enables a high-resolution interrogation of molecular characteristics within specific spatial contexts and tissue morphology. Despite its potential, visualization of ST data is a challenging task due...
12.
Deep Learning of Cell Spatial Organizations Identifies Clinically Relevant Insights in Tissue Images
Wang S, Rong R, Yang D, Zhang X, Zhan X, Bishop J, et al.
Res Sq
. 2023 Jul;
PMID: 37461694
Recent advancements in tissue imaging techniques have facilitated the visualization and identification of various cell types within physiological and pathological contexts. Despite the emergence of cell-cell interaction studies, there is...
13.
Rong R, Wei Y, Li L, Wang T, Zhu H, Xiao G, et al.
EBioMedicine
. 2023 Jul;
94:104698.
PMID: 37453365
Background: Tissues such as the liver lobule, kidney nephron, and intestinal gland exhibit intricate patterns of zonated gene expression corresponding to distinct cell types and functions. To quantitatively understand zonation,...
14.
Wen Z, Lin Y, Wang S, Fujiwara N, Rong R, Jin K, et al.
Genes (Basel)
. 2023 Apr;
14(4).
PMID: 37107679
Polyploidy, the duplication of the entire genome within a single cell, is a significant characteristic of cells in many tissues, including the liver. The quantification of hepatic ploidy typically relies...
15.
Rong R, Sheng H, Jin K, Wu F, Luo D, Wen Z, et al.
Mod Pathol
. 2023 Apr;
36(8):100196.
PMID: 37100227
Microscopic examination of pathology slides is essential to disease diagnosis and biomedical research. However, traditional manual examination of tissue slides is laborious and subjective. Tumor whole-slide image (WSI) scanning is...
16.
Rong R, Wang S, Zhang X, Wen Z, Cheng X, Jia L, et al.
Am J Pathol
. 2023 Jan;
193(4):404-416.
PMID: 36669682
Whole slide imaging is becoming a routine procedure in clinical diagnosis. Advanced image analysis techniques have been developed to assist pathologists in disease diagnosis, staging, subtype classification, and risk stratification....
17.
Wang S, Rong R, Yang D, Fujimoto J, Bishop J, Yan S, et al.
J Clin Invest
. 2023 Jan;
133(2).
PMID: 36647832
Tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR) are effective for many patients with lung cancer with EGFR mutations. However, not all patients are responsive to EGFR TKIs,...
18.
Yang S, Wang S, Wang Y, Rong R, Kim J, Li B, et al.
J Mol Biol
. 2022 Jul;
434(15):167693.
PMID: 35777465
Human microbiome consists of trillions of microorganisms. Microbiota can modulate the host physiology through molecule and metabolite interactions. Integrating microbiome and metabolomics data have the potential to predict different diseases...
19.
Zhang X, Wang S, Rudzinski E, Agarwal S, Rong R, Barkauskas D, et al.
Am J Pathol
. 2022 Apr;
192(6):917-925.
PMID: 35390316
Rhabdomyosarcoma (RMS), the most common malignant soft tissue tumor in children, has several histologic subtypes that influence treatment and predict patient outcomes. Assistance with histologic classification for pathologists as well...
20.
Rong R, Jiang S, Xu L, Xiao G, Xie Y, Liu D, et al.
Gigascience
. 2021 Feb;
10(2).
PMID: 33543271
Background: Trillions of microbes inhabit the human body and have a profound effect on human health. The recent development of metagenome-wide association studies and other quantitative analysis methods accelerate the...