Ruhi Deshmukh
Overview
Explore the profile of Ruhi Deshmukh including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
55
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0
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Recent Articles
1.
Ackermann T, Shokry E, Deshmukh R, Anand J, Galbraith L, Mitchell L, et al.
EMBO Mol Med
. 2024 Oct;
16(11):2749-2774.
PMID: 39433871
The limited availability of therapeutic options for patients with triple-negative breast cancer (TNBC) contributes to the high rate of metastatic recurrence and poor prognosis. Ferroptosis is a type of cell...
2.
Avellino G, Deshmukh R, Rogers S, Charnock-Jones D, Smith G, Tardito S, et al.
Am J Physiol Cell Physiol
. 2023 Mar;
324(4):C878-C885.
PMID: 36878843
Human trophoblast cultures provide powerful tools to model key processes of placental development. In vitro trophoblast studies to date have relied on commercial media that contains nonphysiological levels of nutrients,...
3.
Villar V, Allega M, Deshmukh R, Ackermann T, Nakasone M, Vande Voorde J, et al.
Nat Chem Biol
. 2022 Oct;
19(3):292-300.
PMID: 36280791
Glutamine synthetase (GS) activity is conserved from prokaryotes to humans, where the ATP-dependent production of glutamine from glutamate and ammonia is essential for neurotransmission and ammonia detoxification. Here, we show...
4.
Taurino G, Deshmukh R, Villar V, Chiu M, Shaw R, Hedley A, et al.
Mol Metab
. 2022 Jun;
63:101532.
PMID: 35752287
Bone marrow mesenchymal stromal cells (MSCs) have immunomodulatory and regenerative potential. However, culture conditions govern their metabolic processes and therapeutic efficacy. Here we show that culturing donor-derived MSCs in Plasmax™,...
5.
Deshmukh R, Allega M, Tardito S
Trends Mol Med
. 2021 Sep;
27(11):1045-1059.
PMID: 34489164
The frequent occurrence of neomorphic isocitrate dehydrogenase 1 (IDH1) mutations in low-grade glioma led to an IDH-centric classification of these tumors. However, exploiting metabolic alterations of glioma for diagnostic imaging...
6.
Gonzalez-Menendez P, Romano M, Yan H, Deshmukh R, Papoin J, Oburoglu L, et al.
Cell Rep
. 2021 Feb;
34(5):108723.
PMID: 33535038
The metabolic changes controlling the stepwise differentiation of hematopoietic stem and progenitor cells (HSPCs) to mature erythrocytes are poorly understood. Here, we show that HSPC development to an erythroid-committed proerythroblast...