Ruchika Anand
Overview
Explore the profile of Ruchika Anand including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
29
Citations
1236
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Naha R, Strohm R, Schaumkessel Y, Urbach J, Wittig I, Reichert A, et al.
iScience
. 2024 Dec;
27(12):111467.
PMID: 39720525
The MICOS complex, essential for cristae organization, comprises MIC10 and MIC60 subcomplexes, with MIC13 as a crucial subunit. mutations cause severe mitochondrial hepato-encephalopathy, cristae defects, and MIC10-subcomplex loss. We demonstrate...
2.
Mitochondrial apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways
Damiecki M, Naha R, Schaumkessel Y, Westhoff P, Atanelov N, Stefanski A, et al.
Life Sci Alliance
. 2024 Oct;
7(12).
PMID: 39393820
Mitochondria play central roles in metabolism and metabolic disorders such as type 2 diabetes. MIC26, a mitochondrial contact site and cristae organising system complex subunit, was linked to diabetes and...
3.
Lisowski P, Lickfett S, Rybak-Wolf A, Menacho C, Le S, Pentimalli T, et al.
Nat Commun
. 2024 Aug;
15(1):7027.
PMID: 39174523
Expansion of the glutamine tract (poly-Q) in the protein huntingtin (HTT) causes the neurodegenerative disorder Huntington's disease (HD). Emerging evidence suggests that mutant HTT (mHTT) disrupts brain development. To gain...
4.
Petersilie L, Heiduschka S, Nelson J, Neu L, Le S, Anand R, et al.
iScience
. 2024 Mar;
27(4):109415.
PMID: 38523789
Brain organoids derived from human pluripotent stem cells are a promising tool for studying human neurodevelopment and related disorders. Here, we generated long-term cultures of cortical brain organoid slices (cBOS)...
5.
Golombek M, Tsigaras T, Schaumkessel Y, Hansch S, Weidtkamp-Peters S, Anand R, et al.
Life Sci Alliance
. 2023 Nov;
7(2).
PMID: 37957016
Cristae membranes have been recently shown to undergo intramitochondrial merging and splitting events. Yet, the metabolic and bioenergetic factors regulating them are unclear. Here, we investigated whether and how cristae...
6.
Bueno D, Dey P, Schacht T, Wolf C, Wullner V, Morpurgo E, et al.
Free Radic Biol Med
. 2023 Sep;
208:643-656.
PMID: 37722569
Synaptic signaling depends on ATP generated by mitochondria. Dysfunctional mitochondria shift the redox balance towards a more oxidative environment. Due to extensive connectivity, the striatum is especially vulnerable to mitochondrial...
7.
Peifer-Weiss L, Kurban M, David C, Lubeck M, Kondadi A, Nemer G, et al.
Clin Genet
. 2023 Aug;
104(6):659-668.
PMID: 37649161
APOO/MIC26 is a subunit of the MICOS complex required for mitochondrial cristae morphology and function. Here, we report a novel variant of the APOO/MIC26 gene that causes a severe mitochondrial...
8.
Nakhaei-Rad S, Haghighi F, Bazgir F, Dahlmann J, Busley A, Buchholzer M, et al.
Commun Biol
. 2023 Jun;
6(1):657.
PMID: 37344639
Noonan syndrome (NS), the most common among RASopathies, is caused by germline variants in genes encoding components of the RAS-MAPK pathway. Distinct variants, including the recurrent Ser257Leu substitution in RAF1,...
9.
Lubeck M, Derkum N, Naha R, Strohm R, Driessen M, Belgardt B, et al.
PLoS One
. 2023 Jun;
18(6):e0286756.
PMID: 37279200
Impairments of mitochondrial functions are linked to human ageing and pathologies such as cancer, cardiomyopathy, neurodegeneration and diabetes. Specifically, aberrations in ultrastructure of mitochondrial inner membrane (IM) and factors regulating...
10.
Navaratnarajah T, Bellmann M, Seibt A, Anand R, Degistirici O, Meisel R, et al.
Stem Cell Res Ther
. 2022 Jun;
13(1):256.
PMID: 35715829
The most frequent biochemical defect of inherited mitochondrial disease is isolated complex I deficiency. There is no cure for this disorder, and treatment is mainly supportive. In this study, we...