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Ruben K Dagda

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Articles 60
Citations 6543
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Recent Articles
1.
Chaudary A, Guo Y, Utkin Y, Barancheshmeh M, Dagda R, Gasanoff E
J Membr Biol . 2024 Oct; 258(1):29-46. PMID: 39438323
In this work, the heterodimeric phospholipase A, HDP-2, from viper venom was investigated for its hydrolytic activity in model myelin membranes as well as for its effects on intermembrane exchange...
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Gasanoff E, Dagda R
Toxins (Basel) . 2024 Jul; 16(7). PMID: 39057927
In this paper, we provide an overview of mitochondrial bioenergetics and specific conditions that lead to the formation of non-bilayer structures in mitochondria. Secondly, we provide a brief overview on...
3.
K Soman S, Swain M, Dagda R
Mol Neurobiol . 2024 Jul; 62(2):1756-1769. PMID: 39030441
Brain-derived neurotrophic factor (BDNF) plays a pivotal role in neuronal development, synaptic plasticity, and overall neuronal health by binding to its receptor, tyrosine receptor kinase B (TrkB). This review delves...
4.
Swain M, K Soman S, Tapia K, Dagda R, Dagda R
J Neurochem . 2023 Sep; 167(1):104-125. PMID: 37688457
Brain-derived neurotrophic factor (BDNF) stimulates dendrite outgrowth and synaptic plasticity by activating downstream protein kinase A (PKA) signaling. Recently, BDNF has been shown to modulate mitochondrial respiration in isolated brain...
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Dagda R, Dagda R, Vazquez-Mayorga E, Martinez B, Gallahue A
Int J Mol Sci . 2023 Jan; 24(1). PMID: 36614135
Parkinson's Disease (PD) is a brain-degenerative disorder characterized by a progressive loss of midbrain dopamine neurons. Current standard-of-care includes oral administration of Levodopa to address motor symptoms, but this treatment...
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Sterling K, Dodd G, Alhamdi S, Asimenios P, Dagda R, De Meirleir K, et al.
Int J Mol Sci . 2022 Nov; 23(21). PMID: 36362150
Recent advances in next-generation sequencing (NGS) technologies have opened the door to a wellspring of information regarding the composition of the gut microbiota. Leveraging NGS technology, early metagenomic studies revealed...
8.
Kataoka-Yahiro M, Myaskovsky L, Dagda R, Sood A, Conway K, Guerrero Lopez J, et al.
J Clin Transl Sci . 2022 Aug; 6(1):e83. PMID: 35949659
The Mountain West Clinical Translational Research - Infrastructure Network (MW CTR-IN), established in 2013, is a research network of 13 university partners located among seven Institutional Development Award (IDeA) states...
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K Soman S, Swain M, Dagda R
Methods Mol Biol . 2022 Jun; 2497:349-362. PMID: 35771457
The measurement of mitochondrial function has become imperative to understand and characterize diseases characterized by bioenergetic alterations. The advancement of automation and application of high-throughput technologies has propelled our understanding...
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Fox C, Romenskaia I, Dagda R, Ryan R
Biochim Biophys Acta Biomembr . 2022 Jun; 1864(10):183984. PMID: 35724738
Doxorubicin (DOX) is an aqueous soluble anthracycline therapeutic widely used in cancer treatment. Although DOX anti-cancer activity is dose-dependent, increased dosage enhances the risk of cardiotoxicity. Despite intensive investigation, the...