Roshanak Sharafieh
Overview
Explore the profile of Roshanak Sharafieh including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
125
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0
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Recent Articles
1.
Sharafieh R, Qiao Y, Godlewski I, Czajkowski C, Wu R, Hargis G, et al.
Biosens Bioelectron X
. 2024 Dec;
19.
PMID: 39703931
Continuous glucose monitoring (CGM) using implantable glucose sensors is a critical tool in the management of diabetes. Unfortunately, current commercial glucose sensors have limited performance and lifespans , considered to...
2.
Gasek N, Yan P, Zhu J, Purushothaman K, Kim T, Wang L, et al.
Nat Aging
. 2024 Nov;
5(1):21-27.
PMID: 39537987
While senescent cells have detrimental roles in several contexts, they are highly heterogeneous. p16 highly expressing senescent cells have been reported to exert beneficial functions in wound healing. Here we...
3.
Andrade A, Sun M, Gasek N, Hargis G, Sharafieh R, Xu M
Biology (Basel)
. 2022 Dec;
11(12).
PMID: 36552241
Cellular senescence has gained increasing attention in the field of aging research. Senescent cells have been implicated in biological aging processes, tumorigenesis, development, and wound repair amongst other processes and...
4.
Kesserwan S, Lewis B, Mao L, Sharafieh R, Atwood T, Kreutzer D, et al.
J Pharm Sci
. 2022 Jan;
111(7):1952-1961.
PMID: 34986358
The approximation of euglycemia is the most effective means of preventing diabetic complications, which is achieved through effective insulin delivery. Recent reports indicate that insulin phenolic preservatives, which are found...
5.
Kesserwan S, Mao L, Sharafieh R, Kreutzer D, Klueh U
Drug Deliv Transl Res
. 2021 Sep;
12(7):1711-1718.
PMID: 34561836
Background Extending the lifespan of subcutaneous insulin administration sets and infusion pumps requires overcoming unreliable insulin delivery induced by dermal reactions. All commercially available insulin formulations contain insulin phenolic preservatives...
6.
Lewis B, Mulka A, Mao L, Sharafieh R, Qiao Y, Kesserwan S, et al.
J Diabetes Sci Technol
. 2021 Jul;
17(1):163-171.
PMID: 34286629
Background: Effective exogenous insulin delivery is the cornerstone of insulin dependent diabetes mellitus management. Recent literature indicates that commercial insulin-induced tissue reaction and cellular cytotoxicity may contribute to variability in...
7.
Mulka A, Lewis B, Mao L, Sharafieh R, Kesserwan S, Wu R, et al.
ACS Pharmacol Transl Sci
. 2021 Jun;
4(3):1161-1174.
PMID: 34151206
: Exogenous insulin therapy requires stabilization of the insulin molecule, which is achieved through the use of excipients (e.g., phenolic preservatives (PP)) that provide protein stability, sterility and prolong insulin...
8.
Elgebaly S, Christenson R, Kandil H, El-Khazragy N, Rashed L, Yacoub B, et al.
Biomolecules
. 2021 Mar;
11(3).
PMID: 33670982
Background: Currently, no blood biomarkers exist that can diagnose unstable angina (UA) patients. Nourin is an early inflammatory mediator rapidly released within 5 min by reversible ischemic myocardium, and if...
9.
Barr C, Sharafieh R, Schwarz G, Wu R, Klueh U, Kreutzer D
J Oral Maxillofac Surg
. 2021 Jan;
79(5):1147-1155.
PMID: 33412113
Purpose: The impact of noninflammatory stress, such as aging and pregnancy, on human long bone remodeling is well-established, but little is known about the impact of these stressors on oral...
10.
Kesserwan S, Mulka A, Sharafieh R, Qiao Y, Wu R, Kreutzer D, et al.
J Biomed Mater Res A
. 2020 Sep;
109(7):1065-1079.
PMID: 32896081
Continuous Subcutaneous Insulin Infusion (CSII) is superior to conventional insulin therapy as it improves glycemic control thus reducing the probability of diabetic complications. Notwithstanding CSII's benefits, insulin dependent diabetic patients...