Brianne E Lewis
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Explore the profile of Brianne E Lewis including associated specialties, affiliations and a list of published articles.
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12
Citations
153
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Recent Articles
1.
George S, Kim M, Naik A, Lewis B
Med Sci Educ
. 2024 Jun;
34(3):581-587.
PMID: 38887417
Purpose: When healthcare professionals use biased or stigmatizing language to describe people or conditions, it can impact the quality of care or erode the patient-physician relationship. It is not clear...
2.
Lewis B, Naik A
BMC Med Educ
. 2023 Dec;
23(1):919.
PMID: 38053172
Background: Physician bias refers to the unconscious negative perceptions that physicians have of patients or their conditions. Medical schools and residency programs often incorporate training to reduce biases among their...
3.
Lewis B, Campbell C, Rodrigues A, Thompson L, Pandey A, Gallagher S, et al.
J Biol Inorg Chem
. 2022 Oct;
27(8):759-773.
PMID: 36309885
Mitochondrial [2Fe-2S] cluster biosynthesis is driven by the coordinated activities of the Iron-Sulfur Cluster (ISC) pathway protein machinery. Within the ISC machinery, the protein that provides a structural scaffold on...
4.
Kesserwan S, Lewis B, Mao L, Sharafieh R, Atwood T, Kreutzer D, et al.
J Pharm Sci
. 2022 Jan;
111(7):1952-1961.
PMID: 34986358
The approximation of euglycemia is the most effective means of preventing diabetic complications, which is achieved through effective insulin delivery. Recent reports indicate that insulin phenolic preservatives, which are found...
5.
Lewis B, Mulka A, Mao L, Sharafieh R, Qiao Y, Kesserwan S, et al.
J Diabetes Sci Technol
. 2021 Jul;
17(1):163-171.
PMID: 34286629
Background: Effective exogenous insulin delivery is the cornerstone of insulin dependent diabetes mellitus management. Recent literature indicates that commercial insulin-induced tissue reaction and cellular cytotoxicity may contribute to variability in...
6.
Mulka A, Lewis B, Mao L, Sharafieh R, Kesserwan S, Wu R, et al.
ACS Pharmacol Transl Sci
. 2021 Jun;
4(3):1161-1174.
PMID: 34151206
: Exogenous insulin therapy requires stabilization of the insulin molecule, which is achieved through the use of excipients (e.g., phenolic preservatives (PP)) that provide protein stability, sterility and prolong insulin...
7.
Lewis B, Mason Z, Rodrigues A, Nuth M, Dizin E, Cowan J, et al.
Metallomics
. 2019 Sep;
11(11):1820-1835.
PMID: 31532427
Mitochondrial Fe-S cluster biosynthesis is accomplished within yeast utilizing the biophysical attributes of the "Isu1" scaffold assembly protein. As a member of a highly homologous protein family, Isu1 has sequence...
8.
Tsednee M, Castruita M, Salome P, Sharma A, Lewis B, Schmollinger S, et al.
J Biol Chem
. 2019 Sep;
294(46):17626-17641.
PMID: 31527081
Exposing cells to excess metal concentrations well beyond the cellular quota is a powerful tool for understanding the molecular mechanisms of metal homeostasis. Such improved understanding may enable bioengineering of...
9.
Kuhn E, Naik A, Lewis B, Kokotovich K, Li M, Stemmler T, et al.
Nano Lett
. 2018 Oct;
18(11):7021-7029.
PMID: 30346792
Ions greatly influence protein structure-function and are critical to health and disease. A 10, 000-fold higher calcium in the sarcoplasmic reticulum (SR) of muscle suggests elevated calcium levels near active...
10.
Ruetz M, Kumutima J, Lewis B, Filipovic M, Lehnert N, Stemmler T, et al.
J Biol Chem
. 2017 Mar;
292(16):6512-6528.
PMID: 28246171
Hydrogen sulfide is a critical signaling molecule, but high concentrations cause cellular toxicity. A four-enzyme pathway in the mitochondrion detoxifies HS by converting it to thiosulfate and sulfate. Recent studies...