Robert E Cone
Overview
Explore the profile of Robert E Cone including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
250
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Recent Articles
1.
Cone R, Chattopadhyay S, Pais R, Bhowmick S, Sharafieh R, Lemire Y, et al.
Ophthalmol Eye Dis
. 2013 Jul;
2:57-68.
PMID: 23861614
To determine the origin of peripheral blood mononulclear cells (PBMC) that activate regulatory T cells in anterior chamber-associated immune deviation (ACAID), fluorescein-labeled PBMC were intravenously injected into mice before the...
2.
Cone R, Pais R
Ophthalmol Eye Dis
. 2013 Jul;
1:33-40.
PMID: 23861608
The "immune privilege" that inhibits immune defense mechanisms that could lead to damage to sensitive ocular tissue is based on the expression of immunosuppressive factors on ocular tissue and in...
3.
Pais R, Bhowmick S, Chattopadhyay S, Lemire Y, Sharafieh R, Yadav R, et al.
PLoS One
. 2012 Aug;
7(8):e43182.
PMID: 22912822
Anterior Chamber-Associated Immune Deviation (ACAID) induced by an intracameral injection of antigen generates antigen-specific regulatory splenic T cells that suppress specifically cell-mediated immunity specific for the injected antigen. Circulating F4/80(+)...
4.
Sharafieh R, Lemire Y, Powell S, ORourke J, Cone R
PLoS One
. 2011 Aug;
6(8):e22496.
PMID: 21829628
Background: CD8(+) suppressor T cells exert antigen-specific suppression of the expression of hypersensitivity by activated T cells. Therefore, CD8(+) suppressor T cells serve a major regulatory role for the control...
5.
Bhowmick S, Clark R, Brocke S, Cone R
Int Immunol
. 2011 Jan;
23(2):119-28.
PMID: 21273399
The injection of antigen into the ocular anterior chamber (AC) induces the generation of splenic CD4(+) and CD8(+) regulatory T (Treg) cells, specific for the antigen injected into the AC....
6.
Yadav R, Bhowmick S, Gorecki P, ORourke J, Cone R
PLoS One
. 2010 Aug;
5(8):e11983.
PMID: 20700542
Background: Pertussis toxin (PTX), an exotoxin of Bordetella pertussis, enhances the development of experimental autoimmune diseases such as experimental autoimmune uveitis (EAU) and experimental autoimmune encephalomyelitis (EAE) in rodent models....
7.
Adams C, Housley W, Bhowmick S, Cone R, Rajan T, Forouhar F, et al.
J Immunol
. 2010 Jul;
185(4):2051-8.
PMID: 20624942
Cbl-b is an E3 ubiquitin ligase that negatively regulates T cell activation. Cbl-b(-/-) mice develop spontaneous autoimmunity, and Cbl-b dysregulation has been described in both murine and human autoimmune diseases....
8.
Bhowmick S, Singh A, Flavell R, Clark R, ORourke J, Cone R
J Leukoc Biol
. 2009 Sep;
86(6):1275-83.
PMID: 19741161
CD4(+)FoxP3(+) Tregs are essential mediators of the peripheral immune response to self-antigens. Accordingly, the homeostatic regulation of Treg activity and number would impact on the immune response to both self-...
9.
Cone R, Chattopadhyay S, Sharafieh R, Lemire Y, ORourke J, Flavell R, et al.
Int Immunol
. 2009 Mar;
21(5):567-74.
PMID: 19325036
The introduction of antigen into the anterior chamber (AC) of the eye induces the production of antigen-specific splenic CD8(+) regulatory T cells (AC-SPL cells) that suppress a delayed-type hypersensitivity (DTH)...
10.
Cone R, Chattopadhyay S, Sharafieh R, Lemire Y, ORourke J
Immunol Cell Biol
. 2009 Jan;
87(3):241-8.
PMID: 19139762
The injection of antigen into the anterior chamber (AC, intracameral injection) of a murine eye induces the generation of splenic CD8(+) regulatory T cells (AC-SPL cells) that effect the antigen-specific...