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Rosalind C Williamson

Explore the profile of Rosalind C Williamson including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 306
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Recent Articles
1.
Brooks R, Wei X, Lei M, Cid F, Roper J, Williamson R, et al.
J Mol Cell Biol . 2024 Dec; PMID: 39716457
Upon injury, fibroblasts in the surrounding tissue become activated, migrating into the wound in a controlled manner. Once they arrive, they contract the wound and remodel the stroma. While certain...
2.
Williamson R, Bass M
J Vis Exp . 2015 Oct; (104). PMID: 26484896
In this protocol we demonstrate a method for comparing the competition between GTPase-binding proteins. Such an approach is important for determining the binding capabilities of GTPases for two reasons: The...
3.
Roper J, Williamson R, Bally B, Cowell C, Brooks R, Stephens P, et al.
J Invest Dermatol . 2015 Jun; 135(11):2842-2851. PMID: 26079528
Chronic skin-healing defects are one of the leading challenges to lifelong well-being, affecting 2-5% of populations. Chronic wound formation is linked to age and diabetes and frequently leads to major...
4.
Williamson R, Cowell C, Reville T, Roper J, Rendall T, Bass M
J Biol Chem . 2015 May; 290(25):15437-15449. PMID: 25925950
Sustained directional fibroblast migration requires both polarized activation of the protrusive signal, Rac1, and redistribution of inactive Rac1 from the rear of the cell so that it can be redistributed...
5.
Tilley F, Williamson R, Race P, Rendall T, Bass M
Small GTPases . 2015 Apr; 6(1):36-42. PMID: 25862165
The coronin family of actin-binding proteins regulate actin branching by inhibiting Arp2/3. We recently reported 2 interactions that were unique to coronin-1C: binding of a Rac1 inhibitor, RCC2, to the...
6.
Williamson R, Cowell C, Hammond C, Bergen D, Roper J, Feng Y, et al.
J Cell Sci . 2014 Jul; 127(Pt 19):4292-307. PMID: 25074804
Sustained forward migration through a fibrillar extracellular matrix requires localization of protrusive signals. Contact with fibronectin at the tip of a cell protrusion activates Rac1, and for linear migration it...
7.
Roper J, Williamson R, Bass M
Curr Opin Struct Biol . 2012 Jul; 22(5):583-90. PMID: 22841476
The syndecan family of transmembrane proteoglycans cooperate with integrins to regulate both early and late events in adhesion formation. The heparan sulphate chains substituted on to the syndecan ectodomains are...
8.
Parker M, Qin X, Williamson R, Toye A, Boron W
J Physiol . 2012 Feb; 590(8):2009-34. PMID: 22331414
The renal electrogenic Na(+)/HCO(3)(−) cotransporter (NBCe1-A) contributes to the basolateral step of transepithelial HCO(3)(−) reabsorption in proximal tubule epithelia, contributing to the buffering of blood pH. Elsewhere in the body...
9.
Bass M, Williamson R, Nunan R, Humphries J, Byron A, Morgan M, et al.
Dev Cell . 2011 Oct; 21(4):681-93. PMID: 21982645
Cell migration during wound healing requires adhesion receptor turnover to enable the formation and disassembly of cell-extracellular matrix contacts. Although recent advances have improved our understanding of integrin trafficking pathways,...
10.
Wu F, Saleem M, Kampik N, Satchwell T, Williamson R, Blattner S, et al.
J Am Soc Nephrol . 2010 Jun; 21(9):1456-67. PMID: 20576809
The central role of the multifunctional protein nephrin within the macromolecular complex forming the glomerular slit diaphragm is well established, but the mechanisms linking the slit diaphragm to the cytoskeleton...