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Rongwei Guan

Explore the profile of Rongwei Guan including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 268
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Recent Articles
1.
Yu L, Li Y, Wang H, Wang D, Hao H, Zhang D, et al.
Pathol Res Pract . 2022 Jan; 230:153755. PMID: 34990869
We previously found allelic deletions on chromosomes 17 in primary gastric cancers (GC) using microsatellite markers for loss of heterozygosity (LOH). OVCA1 lies in one of these regions (17q21.33). The...
2.
Wang H, Jiang Y, Yu L, Xu L, Guan R, Cai M, et al.
BMC Gastroenterol . 2021 Sep; 21(1):354. PMID: 34579655
Background: DAL-1 gene was reported to inhibit proliferation, migration, invasion, and epithelial to mesenchymal transition (EMT) of gastric cancer (GC) cells in our previous study. The association between the genomic...
3.
Jia X, Guan R, Cui X, Zhu J, Liu P, Zhang L, et al.
J Cell Mol Med . 2020 Oct; 24(24):14205-14216. PMID: 33124133
Gene amplification chiefly manifests as homogeneously stained regions (HSRs) or double minutes (DMs) in cytogenetically and extrachromosomal DNA (ecDNA) in molecular genetics. Evidence suggests that gene amplification is becoming a...
4.
Dong K, Liu X, Jia X, Miao H, Ji W, Wu J, et al.
Mol Genet Genomic Med . 2020 Sep; 8(11):e1467. PMID: 32970388
Background: Polycystic kidney disease (PKD) is an inherited disease that is life-threatening. Multiple cysts are present in the bilateral kidneys of PKD patients. The progressively enlarged cysts cause structural damage...
5.
Writing Group For Practice Guidelines For Diagnosis And Treatment Of Genetic Diseases Medical Genetics Branch Of Chinese Medical Association , Guan R, Li Q, Fu S
Zhonghua Yi Xue Yi Chuan Xue Za Zhi . 2020 Mar; 37(3):308-312. PMID: 32128749
Rett syndrome (RTT) is a neurodevelopmental disorder mainly affecting the females. It is closely associated with mutations of methylated CpG binding protein 2 ((MeCP2))] gene on the X chromosome. The...
6.
Zaib T, Ji W, Saleem K, Nie G, Li C, Cao L, et al.
BMC Med Genet . 2019 Dec; 20(1):203. PMID: 31870337
Background: Synpolydactyly type 1 (SPD1), also known as syndactyly type II, is an autosomal dominant limb deformity generally results in webbing of 3rd and 4th fingers, duplication of 4th or...
7.
Dong K, Miao H, Jia X, Wu J, Wu H, Sun J, et al.
Mol Med Rep . 2019 Feb; 19(4):2671-2679. PMID: 30720121
Polycystic kidney disease (PKD) is a life‑threatening inherited disease with a morbidity of 1:500‑1,000 worldwide. Numerous progressively enlarging cysts are observed in the bilateral kidneys of patients with PKD, inducing...
8.
Cai M, Zhang H, Hou L, Gao W, Song Y, Cui X, et al.
Int J Cancer . 2018 Aug; 144(5):1037-1048. PMID: 30070702
Gene amplification, which involves the two major topographical structures double minutes (DMs) and homegeneously stained region (HSR), is a common mechanism of treatment resistance in cancer and is initiated by...
9.
Guan R, Peng L, Wang D, He H, Wang D, Zhang R, et al.
Oncotarget . 2017 Nov; 8(43):75243-75253. PMID: 29088861
TOB1, a member of the BTG/TOB protein family, inhibits tumor cell proliferation. We previously observed down-regulation and phosphorylation of TOB1 in gastric cancer (GC). Here, we examined the subcellular distribution...
10.
Pang B, Wu N, Guan R, Pang L, Li X, Li S, et al.
Clin Cancer Res . 2017 Jun; 23(18):5598-5610. PMID: 28606921
Investigate the role of regulator of chromosome condensation 2 () on lung adenocarcinoma (LUAD) metastasis. Clinical specimens were used to assess the impact of RCC2 on LUAD metastasis. Mouse models,...