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Ronald P van Rij

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Articles 102
Citations 3298
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Recent Articles
1.
Qu J, Schinkel M, Chiggiato L, Rosendo Machado S, Overheul G, Miesen P, et al.
Commun Biol . 2025 Jan; 8(1):123. PMID: 39863754
Aedes mosquitoes transmit pathogenic arthropod-borne (arbo) viruses, putting nearly half the world's population at risk. Blocking virus replication in mosquitoes is a promising approach to prevent arbovirus transmission, the development...
2.
Willemsen W, Helmes N, Overheul G, Henkens M, Spruijt R, van Rij R, et al.
One Health . 2025 Jan; 20():100960. PMID: 39845567
Millions of people are annually infected by mosquito-transmitted arboviruses including dengue virus (DENV), West Nile virus (WNV), Zika virus (ZIKV) and chikungunya virus (CHIKV). Insect-specific flaviviruses (ISFs), which only infect...
3.
Besson B, Overheul G, Wolfinger M, Junglen S, van Rij R
J Virol . 2024 Oct; 98(11):e0121524. PMID: 39404457
RNA interference (RNAi) plays an essential role in mosquito antiviral immunity, but it is not known whether viral small interfering RNA (siRNA) profiles differ between mosquito-borne and mosquito-specific viruses. A...
4.
Haase A, Ketting R, Lai E, van Rij R, Siomi M, Svoboda P, et al.
EMBO J . 2024 Sep; 43(22):5335-5339. PMID: 39327528
No abstract available.
5.
Schinkel M, Bousema T, van Rij R
Curr Opin Insect Sci . 2024 Jun; 64:101222. PMID: 38908822
Mosquito-borne diseases have a major impact on global human health. Biological agents that colonize the mosquito vector are increasingly explored as an intervention strategy to prevent vector-borne disease transmission. For...
6.
Lezcano O, Fuhrmann L, Ramakrishnan G, Beerenwinkel N, Huynen M, van Rij R
Virus Evol . 2024 Jan; 9(2):vead074. PMID: 38162315
Virus evolution is strongly affected by antagonistic co-evolution of virus and host. Host immunity positively selects for viruses that evade the immune response, which in turn may drive counter-adaptations in...
7.
Boby M, Fearon D, Ferla M, Filep M, Koekemoer L, Robinson M, et al.
Science . 2023 Nov; 382(6671):eabo7201. PMID: 37943932
We report the results of the COVID Moonshot, a fully open-science, crowdsourced, and structure-enabled drug discovery campaign targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease. We discovered...
8.
Fohse K, Geckin B, Zoodsma M, Kilic G, Liu Z, Roring R, et al.
Clin Immunol . 2023 Sep; 255:109762. PMID: 37673225
The mRNA-based BNT162b2 protects against severe disease and mortality caused by SARS-CoV-2 via induction of specific antibody and T-cell responses. Much less is known about its broad effects on immune...
9.
Qu J, Betting V, van Iterson R, Kwaschik F, van Rij R
Cell Rep . 2023 Mar; 42(3):112257. PMID: 36930642
The piRNA pathway in mosquitoes differs substantially from other model organisms, with an expanded PIWI gene family and functions in antiviral defense. Here, we define core piRNA clusters as genomic...
10.
Moonen J, Schinkel M, van der Most T, Miesen P, van Rij R
One Health . 2023 Feb; 16:100490. PMID: 36817977
Mosquitoes are vectors for emerging and re-emerging infectious viral diseases of humans, livestock and other animals. In addition to these arthropod-borne (arbo)viruses, mosquitoes are host to an array of insect-specific...