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Rona MacKie

Explore the profile of Rona MacKie including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 864
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Recent Articles
1.
Walter F, Birt L, Cavers D, Scott S, Emery J, Burrows N, et al.
BMJ Open . 2014 Jul; 4(7):e005566. PMID: 25052174
Objective: To explore symptom appraisal and help-seeking decisions among patients recently diagnosed with melanomas, and to compare experiences of people with 'thinner' (<1 mm) and 'thicker' (>2 mm) melanomas, as...
2.
Barrett J, Iles M, Harland M, Taylor J, Aitken J, Andresen P, et al.
Nat Genet . 2011 Oct; 43(11):1108-13. PMID: 21983787
We report a genome-wide association study for melanoma that was conducted by the GenoMEL Consortium. Our discovery phase included 2,981 individuals with melanoma and 1,982 study-specific control individuals of European...
3.
Macgregor S, Montgomery G, Liu J, Zhao Z, Henders A, Stark M, et al.
Nat Genet . 2011 Oct; 43(11):1114-8. PMID: 21983785
We performed a genome-wide association study of melanoma in a discovery cohort of 2,168 Australian individuals with melanoma and 4,387 control individuals. In this discovery phase, we confirm several previously...
4.
Olsen C, Zens M, Green A, Stukel T, Holman C, Mack T, et al.
Int J Cancer . 2010 Sep; 129(3):713-23. PMID: 20857492
A model has been proposed whereby melanomas arise through two distinct pathways dependent on the relative influence of host susceptibility and sun exposure. Such pathways may explain site-specific patterns of...
5.
Bishop D, Demenais F, Iles M, Harland M, Taylor J, Corda E, et al.
Nat Genet . 2009 Jul; 41(8):920-5. PMID: 19578364
We report a genome-wide association study of melanoma conducted by the GenoMEL consortium based on 317K tagging SNPs for 1,650 selected cases and 4,336 controls, with replication in an additional...
6.
Bottomley A, Coens C, Suciu S, Santinami M, Kruit W, Testori A, et al.
J Clin Oncol . 2009 May; 27(18):2916-23. PMID: 19433686
Purpose: Interferon (IFN) -based adjuvant therapy in melanoma is associated with significant side effects, which necessitates evaluation of health-related quality of life (HRQOL). Our trial examined the HRQOL effects of...
7.
Eggermont A, Suciu S, Santinami M, Testori A, Kruit W, Marsden J, et al.
Lancet . 2008 Jul; 372(9633):117-126. PMID: 18620949
Background: Any benefit of adjuvant interferon alfa-2b for melanoma could depend on dose and duration of treatment. Our aim was to determine whether pegylated interferon alfa-2b can facilitate prolonged exposure...
8.
Elliott B, Scolyer R, Suciu S, Lebecque S, Rimoldi D, Gugerli O, et al.
Clin Cancer Res . 2007 Jul; 13(13):3825-30. PMID: 17606713
Purpose: In a previous immunohistochemical study of dendritic cells (DC) in sentinel lymph nodes (SLN) draining regressing melanomas, we found that the accumulation of mature DC-LAMP(+) DCs in SLNs was...
9.
Lang J, Hayward N, Goldgar D, Tsao H, Hogg D, Palmer J, et al.
Genes Chromosomes Cancer . 2006 Dec; 46(3):277-87. PMID: 17171691
Germline mutations in the tumor suppressor gene CDKN2A have been shown to predispose to cutaneous malignant melanoma. The M53I mutation is the most common CDKN2A mutation identified in Scottish melanoma...
10.
Kettlewell S, Moyes C, Bray C, Soutar D, Mackay A, Byrne D, et al.
BMJ . 2006 Jun; 332(7555):1423. PMID: 16735303
Objective: To establish the prognostic value of knowledge of sentinel node status in melanoma. Design: Single centre prospective observational study, with sentinel nodes identified by lymphoscintigraphy, gamma probe, and intraoperative...