Romit Chakrabarty
Overview
Explore the profile of Romit Chakrabarty including associated specialties, affiliations and a list of published articles.
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15
Citations
685
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Recent Articles
1.
Mahalingam D, Goel S, Aparo S, Arora S, Noronha N, Tran H, et al.
Cancers (Basel)
. 2018 May;
10(6).
PMID: 29799479
Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis, with 1 and 5-year survival rates of ~18% and 7% respectively. FOLFIRINOX or gemcitabine in combination with nab-paclitaxel are standard treatment options...
2.
Mahalingam D, Fountzilas C, Moseley J, Noronha N, Tran H, Chakrabarty R, et al.
Cancer Chemother Pharmacol
. 2017 Mar;
79(4):697-703.
PMID: 28289863
REOLYSIN (pelareorep) is an investigational new drug, consisting of a live, replication-competent, Reovirus Type 3 Dearing strain in a proprietary formulation. Several preclinical and clinical trials with REOLYSIN on a...
3.
Chakrabarty R, Tran H, Selvaggi G, Hagerman A, Thompson B, Coffey M
Invest New Drugs
. 2015 Feb;
33(3):761-74.
PMID: 25693885
Pelareorep (REOLYSIN®) is an investigational new drug, a proprietary formulation consisting of a live, replication-competent, naturally occurring Reovirus Type 3 Dearing strain. Through several preclinical studies it was determined that...
4.
Chakrabarty R, Qu Y, Ro D
Phytochemistry
. 2015 Jan;
113:121-9.
PMID: 25553584
Natural rubber, cis-1,4-polyisoprene, is an important raw material in chemical industries, but its biosynthetic mechanism remains elusive. Natural rubber is known to be synthesized in rubber particles suspended in laticifer...
5.
Qu Y, Chakrabarty R, Tran H, Kwon E, Kwon M, Nguyen T, et al.
J Biol Chem
. 2014 Dec;
290(4):1898-914.
PMID: 25477521
Natural rubber (cis-1,4-polyisoprene) is an indispensable biopolymer used to manufacture diverse consumer products. Although a major source of natural rubber is the rubber tree (Hevea brasiliensis), lettuce (Lactuca sativa) is...
6.
Chakrabarty R, Tran H, Fortin Y, Yu Z, Shen S, Kolman J, et al.
Appl Microbiol Biotechnol
. 2014 Jan;
98(4):1763-70.
PMID: 24419798
REOLYSIN (pelareorep) is a proprietary isolate of the reovirus T3D (Type 3 Dearing) strain which is currently being tested in clinical trials as an anticancer therapeutic agent. Reovirus genomes are...
7.
Chakrabarty R, Tran H, Boulay I, Moran T, Parenteau A, Tavcar R, et al.
Invest New Drugs
. 2013 Oct;
31(6):1476-86.
PMID: 24121993
Numerous pre-clinical and clinical studies on reovirus have generated valuable information which supports the use of this orphan virus as an investigational drug for cancer treatment. Reolysin® (pelareorep) is a...
8.
Josephrajkumar A, Chakrabarty R, Thomas G
Indian J Biochem Biophys
. 2013 Aug;
42(4):243-5.
PMID: 23923549
Occurrence of trypsin-like protease in fresh cardamom (Elettaria cardamomum Maton) seeds, as evidenced by the benzoyl-arg-p-nitroanilide (BApNA) hydrolyzing ability of the seed enzyme preparation under alkaline condition is reported for...
9.
Xiao M, Zhang Y, Chen X, Lee E, Barber C, Chakrabarty R, et al.
J Biotechnol
. 2013 Apr;
166(3):122-34.
PMID: 23602801
Plants produce a vast array of specialized metabolites, many of which are used as pharmaceuticals, flavors, fragrances, and other high-value fine chemicals. However, most of these compounds occur in non-model...
10.
Andersson D, Chakrabarty R, Bejai S, Zhang J, Rask L, Meijer J
Phytochemistry
. 2009 Aug;
70(11-12):1345-54.
PMID: 19703694
Myrosinases (EC 3.2.1.147) are beta-thioglucoside glucosidases present in Brassicaceae plants. These enzymes serve to protect plants against pathogens and insect pests by initiating breakdown of the secondary metabolites glucosinolates into...