Roland Contreras
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Explore the profile of Roland Contreras including associated specialties, affiliations and a list of published articles.
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44
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1956
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Recent Articles
11.
Fontanella G, De Vusser K, Laroy W, Daurelio L, Nocito A, Revelli S, et al.
Vaccine
. 2008 Apr;
26(19):2322-34.
PMID: 18403070
Chagas' disease is a major tropical disease for which a cure for chronic phase does not exist yet. Trypanosoma cruzi trans-sialidase (TS) seems to be involved in relevant processes such...
12.
Liu X, Desmyter L, Gao C, Laroy W, Dewaele S, Vanhooren V, et al.
Zhonghua Gan Zang Bing Za Zhi
. 2008 Jan;
16(1):74-5.
PMID: 18226355
No abstract available.
13.
Ryckaert S, Callewaert N, Jacobs P, Dewaele S, Dewerte I, Contreras R
Glycobiology
. 2007 Dec;
18(2):137-44.
PMID: 18086821
The establishment of a robust technology platform for the expression cloning of carbohydrate-binding proteins remains a key challenge in glycomics. Here we explore the utility of using yeast surface display...
14.
Vanhooren V, Desmyter L, Liu X, Cardelli M, Franceschi C, Federico A, et al.
Rejuvenation Res
. 2007 Dec;
10(4):521-531a.
PMID: 18047421
N-glycan profiling of the human serum glycoproteins including immunoglobulin fraction on different age groups of healthy persons shows substantial changes with increasing age in three major N-glycan structures. In individuals...
15.
Vervecken W, Callewaert N, Kaigorodov V, Geysens S, Contreras R
Methods Mol Biol
. 2007 Oct;
389:119-38.
PMID: 17951639
Glycosylation is an important issue in heterologous protein production for therapeutic applications. Glycoproteins produced in Pichia pastoris contain high mannose glycan structures that can hamper downstream processing, might be immunogenic,...
16.
Liu X, Desmyter L, Gao C, Laroy W, Dewaele S, Vanhooren V, et al.
Hepatology
. 2007 Aug;
46(5):1426-35.
PMID: 17683101
Unlabelled: We evaluated the use of blood serum N-glycan fingerprinting as a tool for the diagnosis of hepatocellular carcinoma (HCC) in patients with cirrhosis induced by hepatitis B virus (HBV)....
17.
Chen C, Contreras R
Methods Mol Biol
. 2007 Jul;
371:237-48.
PMID: 17634586
We developed a high-throughput functional genomic screening system that allows identification of genes prolonging lifespan in the baker's yeast Saccharomyces cerevisiae. The method is based on isolating yeast mother cells...
18.
Desmyter L, Fan Y, Praet M, Jaworski T, Vervecken W, de Hemptinne B, et al.
J Gastroenterol Hepatol
. 2007 Jul;
22(7):1148-54.
PMID: 17608861
Background: Non-invasive staging of human liver fibrosis is a desirable objective that remains under extensive evaluation. Animal model systems are often used for studying human liver disease and screening antifibrotic...
19.
Desmyter L, Verstraelen J, Dewaele S, Libert C, Contreras R, Chen C
Biogerontology
. 2007 Apr;
8(5):527-35.
PMID: 17415679
In this study, we used our recently developed screening method, Bud-Scar-based Screening (BSS), to screen a yeast cDNA expression library in an SGS1 deletion BY4742 yeast strain. One gene involved...
20.
Laroy W, Contreras R, Callewaert N
Nat Protoc
. 2007 Apr;
1(1):397-405.
PMID: 17406262
Here we provide a detailed protocol for the analysis of protein-linked glycans on DNA sequencing equipment. This protocol satisfies the glyco-analytical needs of many projects and can form the basis...