Rola Al Sayegh
Overview
Explore the profile of Rola Al Sayegh including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
24
Followers
0
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Recent Articles
1.
Gilgenkrantz H, Sayegh R, Lotersztajn S
Annu Rev Pharmacol Toxicol
. 2024 Sep;
65(1):281-299.
PMID: 39259981
Liver fibrosis develops in response to chronic liver injury and is characterized by a sustained inflammatory response that leads to excessive collagen deposition by myofibroblasts. The fibrogenic response is governed...
2.
Allaire M, Sayegh R, Mabire M, Hammoutene A, Siebert M, Caer C, et al.
JHEP Rep
. 2023 Jul;
5(8):100794.
PMID: 37520673
Background & Aims: Liver regeneration is a repair process in which metabolic reprogramming of parenchymal and inflammatory cells plays a major role. Monoacylglycerol lipase (MAGL) is an ubiquitous enzyme at...
3.
Mabire M, Hegde P, Hammoutene A, Wan J, Caer C, Sayegh R, et al.
Nat Commun
. 2023 Apr;
14(1):1830.
PMID: 37005415
Recent data have shown that liver fibrosis can regress even at later stages of cirrhosis and shifting the immune response from pro-inflammatory towards a resolutive profile is considered as a...
4.
Jaffa A, Jaffa M, Moussa M, Ahmed I, Karam M, Aldeen K, et al.
Front Pharmacol
. 2021 Dec;
12:743059.
PMID: 34867349
Microglia, the resident phagocytes of the central nervous system and one of the key modulators of the innate immune system, have been shown to play a major role in brain...
5.
Ahmed I, Jaffa M, Moussa M, Hatem D, El-Achkar G, Sayegh R, et al.
Front Pharmacol
. 2021 Sep;
12:715111.
PMID: 34566641
The occurrence and persistence of hepatic injury which arises from cell death and inflammation result in liver disease. The processes that lead to liver injury progression and resolution are still...