Rohit N Kulkarni
Overview
Explore the profile of Rohit N Kulkarni including associated specialties, affiliations and a list of published articles.
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214
Citations
8120
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Recent Articles
1.
Xiao L, De Jesus D, Ju C, Wei J, Hu J, DiStefano-Forti A, et al.
Nat Commun
. 2025 Jan;
16(1):533.
PMID: 39788955
N-methyladenosine (mA) is among the most abundant mRNA modifications, yet its cell-type-specific regulatory roles remain unclear. Here we show that mA methyltransferase-like 14 (METTL14) differentially regulates transcriptome in brown versus...
2.
Okagawa S, Sakaguchi M, Okubo Y, Takekuma Y, Igata M, Kondo T, et al.
Nat Commun
. 2024 Nov;
15(1):9585.
PMID: 39532838
Lipodystrophy and obesity are associated with insulin resistance and metabolic syndrome accompanied by fat tissue dysregulation. Here, we show that serine protease inhibitor A1 (SerpinA1) expression in the liver is...
3.
Swensen A, Piehowski P, Chen J, Chan X, Kelly S, Petyuk V, et al.
bioRxiv
. 2024 Sep;
PMID: 39345556
Aims/hypothesis: Progression to type 1 diabetes (T1D) is associated with genetic factors, the presence of autoantibodies, and a decline in β cell insulin secretion in response to glucose. Very little...
4.
Kahraman S, De Jesus D, Wei J, Brown N, Zou Z, Hu J, et al.
EMBO J
. 2024 Sep;
43(22):5445-5468.
PMID: 39322760
N-methyladenosine (mA) is the most abundant chemical modification in mRNA and plays important roles in human and mouse embryonic stem cell pluripotency, maintenance, and differentiation. We have recently reported that...
5.
Xiao L, De Jesus D, Ju C, Wei J, Hu J, DiStefano-Forti A, et al.
Cell Metab
. 2024 Sep;
36(10):2207-2227.e9.
PMID: 39255799
Brown adipose tissue (BAT) regulates systemic metabolism by releasing signaling lipids. N-methyladenosine (mA) is the most prevalent and abundant post-transcriptional mRNA modification and has been reported to regulate BAT adipogenesis...
6.
7.
Sabadell-Basallote J, Astiarraga B, Castano C, Ejarque M, Repolles-de-Dalmau M, Quesada I, et al.
J Clin Invest
. 2024 May;
134(12).
PMID: 38713514
Pancreatic β cell dysfunction is a key feature of type 2 diabetes, and novel regulators of insulin secretion are desirable. Here, we report that succinate receptor 1 (SUCNR1) is expressed...
8.
De Jesus D, Zhang Z, Brown N, Li X, Xiao L, Hu J, et al.
Nat Cell Biol
. 2024 Feb;
26(3):421-437.
PMID: 38409327
Type 1 diabetes (T1D) is characterized by the destruction of pancreatic β-cells. Several observations have renewed the interest in β-cell RNA sensors and editors. Here, we report that -methyladenosine (mA)...
9.
Mirmira R, Kulkarni R, Xu P, Drossos T, Varady K, Knutson K, et al.
J Clin Transl Sci
. 2024 Jan;
7(1):e263.
PMID: 38229904
Stress and diabetes coexist in a vicious cycle. Different types of stress lead to diabetes, while diabetes itself is a major life stressor. This was the focus of the Chicago...
10.
Xi Y, Liu S, Bettaieb A, Matsuo K, Matsuo I, Hosein E, et al.
Diabetologia
. 2023 Oct;
67(1):215.
PMID: 37861718
No abstract available.