Roel P H De Maeyer
Overview
Explore the profile of Roel P H De Maeyer including associated specialties, affiliations and a list of published articles.
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16
Citations
474
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Recent Articles
1.
Bracken O, De Maeyer R, Akbar A
Nat Rev Drug Discov
. 2025 Jan;
PMID: 39875569
Immunity declines with age. This results in a higher risk of age-related diseases, diminished ability to respond to new infections and reduced response to vaccines. The causes of this immune...
2.
Collins G, de Souza Carvalho J, Jayasinghe S, Gumuliauskaite U, Lowe D, Thomas D, et al.
J Leukoc Biol
. 2024 Oct;
117(2).
PMID: 39412158
Phagocytosis is an important leukocyte function; however, using existing models it cannot be measured in human tissues in vivo. To address this, we characterized a new phagocytosis model using intradermal...
3.
Feehan K, Bridgewater H, Stenkiewicz-Witeska J, De Maeyer R, Ferguson J, Mack M, et al.
Nat Commun
. 2024 May;
15(1):4326.
PMID: 38773113
Resolving inflammation is thought to return the affected tissue back to homoeostasis but recent evidence supports a non-linear model of resolution involving a phase of prolonged immune activity. Here we...
4.
Pearce D, Akarca A, De Maeyer R, Kostina E, Huebner A, Sivakumar M, et al.
Front Oncol
. 2023 Jun;
13:1156743.
PMID: 37342197
Background: Patient-derived xenograft (PDX) models involve the engraftment of tumour tissue in immunocompromised mice and represent an important pre-clinical oncology research method. A limitation of non-small cell lung cancer (NSCLC)...
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Maini A, Becares N, China L, Tittanegro T, Patel A, De Maeyer R, et al.
JHEP Rep
. 2021 Nov;
3(6):100332.
PMID: 34825153
Background & Aims: Infection is a major problem in advanced liver disease secondary to monocyte dysfunction. Elevated prostaglandin (PG)E is a mediator of monocyte dysfunction in cirrhosis; thus, we examined...
8.
De Maeyer R, Chambers E
Immunol Lett
. 2020 Dec;
230:1-10.
PMID: 33309673
Ageing is a global burden. Increasing age is associated with increased incidence of infections and cancer and decreased vaccine efficacy. This increased morbidity observed with age, is believed to be...
9.
Gilroy D, De Maeyer R, Tepper M, OBrien A, Uddin M, Chen J, et al.
Pharmacol Ther
. 2020 Nov;
221:107745.
PMID: 33188794
While COVID-19, the disease driven by SARS-CoV-2 has ignited interest in the host immune response to this infection, it has also highlighted the lack of treatment options for the damaging...
10.
Covre L, De Maeyer R, Gomes D, Akbar A
Aging Cell
. 2020 Nov;
19(12):e13272.
PMID: 33166035
The development of senescence in tissues of different organs and in the immune system are usually investigated independently of each other although during ageing, senescence in both cellular systems develop...