Daniel R Goldstein
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Explore the profile of Daniel R Goldstein including associated specialties, affiliations and a list of published articles.
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108
Citations
3856
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Recent Articles
1.
Luna A, Chou K, Wragg K, Worley M, Paruchuri N, Zhou X, et al.
Aging Cell
. 2025 Jan;
:e14437.
PMID: 39754380
Aging is a major risk factor for poor outcomes following respiratory infections. In animal models, the most severe outcomes of respiratory infections in older hosts have been associated with an...
2.
Wang H, Kazaleh M, Gioscia-Ryan R, Millar J, Temprano-Sagrera G, Wood S, et al.
bioRxiv
. 2024 Nov;
PMID: 39554010
Abdominal aortic aneurysms (AAAs) are a degenerative aortic disease and associated with hallmarks of aging, such as mitophagy. Despite this, the exact associations among mitophagy, aging, and AAA progression remain...
3.
Ponce-Balbuena D, Tyrrell D, Cruz-Cortes C, Guerrero-Serna G, Monteiro da Rocha A, Herron T, et al.
bioRxiv
. 2024 Aug;
PMID: 39149279
Obesity is a major risk factor for atrial fibrillation (AF) the most common serious cardiac arrhythmia, but the molecular mechanisms underlying diet-induced AF remain unclear. In this study, we subjected...
4.
Wragg K, Worley M, Deng J, Salmon M, Goldstein D
Am J Transplant
. 2024 Aug;
24(12):2174-2186.
PMID: 39142471
Alterations in mitochondrial function and associated quality control programs, including mitochondrial-specific autophagy, termed mitophagy, are gaining increasing recognition in the context of disease. However, the role of mitophagy in organ...
5.
Hill B, Zak A, Raja S, Bugada L, Rizvi S, Roslan S, et al.
JCI Insight
. 2024 May;
9(12).
PMID: 38814732
Influenza poses a persistent health burden worldwide. To design equitable vaccines effective across all demographics, it is essential to better understand how host factors such as genetic background and aging...
6.
Tyrrell D, Wragg K, Chen J, Wang H, Song J, Blin M, et al.
Nat Aging
. 2024 May;
4(8):1166.
PMID: 38789547
No abstract available.
7.
Urie R, Morris A, Farris D, Hughes E, Xiao C, Chen J, et al.
Sci Adv
. 2024 May;
10(20):eadk6178.
PMID: 38748794
Invasive graft biopsies assess the efficacy of immunosuppression through lagging indicators of transplant rejection. We report on a microporous scaffold implant as a minimally invasive immunological niche to assay rejection...
8.
Song J, Zhang Y, Frieler R, Andren A, Wood S, Tyrrell D, et al.
J Clin Invest
. 2023 Dec;
134(3).
PMID: 38085578
Itaconate has emerged as a critical immunoregulatory metabolite. Here, we examined the therapeutic potential of itaconate in atherosclerosis. We found that both itaconate and the enzyme that synthesizes it, aconitate...
9.
Tyrrell D, Wragg K, Chen J, Wang H, Song J, Blin M, et al.
Nat Aging
. 2023 Nov;
3(12):1576-1590.
PMID: 37996758
Aging is a strong risk factor for atherosclerosis and induces accumulation of memory CD8 T cells in mice and humans. Biological changes that occur with aging lead to enhanced atherosclerosis,...
10.
Goldstein D
J Heart Lung Transplant
. 2023 Jul;
42(10):1319-1320.
PMID: 37410000
No abstract available.