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Rocio Espada

Explore the profile of Rocio Espada including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 123
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Recent Articles
1.
Gines G, Espada R, Drame-Maigne A, Baccouche A, Larrouy N, Rondelez Y
Nat Nanotechnol . 2024 Feb; 19(6):800-809. PMID: 38409552
The analysis of proteins at the single-molecule level reveals heterogeneous behaviours that are masked in ensemble-averaged techniques. The digital quantification of enzymes traditionally involves the observation and counting of single...
2.
Drame-Maigne A, Espada R, McCallum G, Sieskind R, Gines G, Rondelez Y
ACS Synth Biol . 2024 Jan; 13(2):474-484. PMID: 38206581
Directed evolution provides a powerful route for enzyme engineering. State-of-the-art techniques functionally screen up to millions of enzyme variants using high throughput microfluidic sorters, whose operation remains technically challenging. Alternatively,...
3.
Espada R, Zarevski N, Drame-Maigne A, Rondelez Y
Gigascience . 2022 Nov; 11. PMID: 36352541
Background: Nanopore technologies allow high-throughput sequencing of long strands of DNA at the cost of a relatively large error rate. This limits its use in the reading of amplicon libraries...
4.
Marchi J, Galpern E, Espada R, Ferreiro D, Walczak A, Mora T
PLoS Comput Biol . 2019 Aug; 15(8):e1007282. PMID: 31415557
The coding space of protein sequences is shaped by evolutionary constraints set by requirements of function and stability. We show that the coding space of a given protein family-the total...
5.
Espada R, Olaya-Ponzone L, Haasova L, Martin E, Garcia-Gomez J
PLoS One . 2019 Apr; 14(4):e0215020. PMID: 30990845
A case of intergeneric hybridization in the wild between a female bottlenose dolphin (Tursiops truncatus) and a short-beaked common dolphin (Delphinus delphis), considered members of 'vulnerable' and 'endangered' subpopulations in...
6.
Glavina J, Roman E, Espada R, de Prat-Gay G, Chemes L, Sanchez I
Virology . 2018 Sep; 525:117-131. PMID: 30265888
E1A is the main transforming protein in mastadenoviruses. This work uses bioinformatics to extrapolate experimental knowledge from Human adenovirus serotype 5 and 12 E1A proteins to all known serotypes. A...
7.
Espada R, Parra R, Mora T, Walczak A, Ferreiro D
PLoS Comput Biol . 2017 Jun; 13(6):e1005584. PMID: 28617812
Natural protein sequences contain a record of their history. A common constraint in a given protein family is the ability to fold to specific structures, and it has been shown...
8.
Espada R, Sanchez I, Ferreiro D
Biophys J . 2016 Dec; 111(11):2339-2341. PMID: 27926834
No abstract available.
9.
Turjanski P, Parra R, Espada R, Becher V, Ferreiro D
Sci Rep . 2016 Apr; 6:23959. PMID: 27044676
Some natural proteins display recurrent structural patterns. Despite being highly similar at the tertiary structure level, repeating patterns within a single repeat protein can be extremely variable at the sequence...
10.
Parra R, Espada R, Verstraete N, Ferreiro D
PLoS Comput Biol . 2015 Dec; 11(12):e1004659. PMID: 26691182
Ankyrin repeat containing proteins are one of the most abundant solenoid folds. Usually implicated in specific protein-protein interactions, these proteins are readily amenable for design, with promising biotechnological and biomedical...