Robyn P Hickerson
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Explore the profile of Robyn P Hickerson including associated specialties, affiliations and a list of published articles.
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33
Citations
1166
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Recent Articles
1.
Conneely M, Namkoong J, Allison F, Hirata Tsutsumi S, Grussu D, Willis R, et al.
JID Innov
. 2024 Oct;
5(1):100305.
PMID: 39403555
A tensioned ex vivo full-thickness human skin explant platform was used to assess the bioeffects arising from application of several commercial chemexfoliation agents. Although such treatments are well-established, and improved...
2.
OToole E, Kelsell D, Caterina M, de Brito M, Hansen D, Hickerson R, et al.
J Invest Dermatol
. 2023 Dec;
144(4):748-754.
PMID: 38099888
Pachyonychia congenita (PC) is a dominantly inherited genetic disorder of cornification. PC stands out among other genodermatoses because despite its rarity, it has been the focus of a very large...
3.
Vermeer F, Bremer J, Sietsma R, Sandilands A, Hickerson R, Bolling M, et al.
Int J Mol Sci
. 2021 Nov;
22(22).
PMID: 34830104
Epidermolysis bullosa is a group of genetic skin conditions characterized by abnormal skin (and mucosal) fragility caused by pathogenic variants in various genes. The disease severity ranges from early childhood...
4.
Fu D, Allen E, Hickerson R, Leslie Pedrioli D, McLean W
Transl Vis Sci Technol
. 2021 Jan;
9(13):44.
PMID: 33442498
Purpose: The purpose of this study was to develop and characterize a novel bioluminescence transgenic mouse model that facilitates rapid evaluation of genetic medicine delivery methods for inherited and acquired...
5.
Allen E, Courtney D, Atkinson S, Moore J, Mairs L, Poulsen E, et al.
Hum Mol Genet
. 2016 Jan;
25(6):1176-91.
PMID: 26758872
Meesmann epithelial corneal dystrophy (MECD) is a rare autosomal dominant disorder caused by dominant-negative mutations within the KRT3 or KRT12 genes, which encode the cytoskeletal protein keratins K3 and K12,...
6.
Kaspar R, Hickerson R, Gonzalez-Gonzalez E, Flores M, Speaker T, Rogers F, et al.
Methods Mol Biol
. 2015 Nov;
1372:1-24.
PMID: 26530911
Monogenic skin diseases arise from well-defined single gene mutations, and in some cases a single point mutation. As the target cells are superficial, these diseases are ideally suited for treatment...
7.
Hickerson R, Speaker T, Lara M, Gonzalez-Gonzalez E, Flores M, Contag C, et al.
Mol Imaging Biol
. 2015 Jul;
18(1):34-42.
PMID: 26169581
Purpose: Small interfering RNAs (siRNAs) specifically and potently inhibit target gene expression. Pachyonychia congenita (PC) is a skin disorder caused by mutations in genes encoding keratin (K) 6a/b, K16, and...
8.
Cao Y, Hickerson R, Seegmiller B, Grapov D, Gross M, Bessette M, et al.
J Dermatol Sci
. 2015 Feb;
77(3):156-65.
PMID: 25656049
Background: Pachyonychia congenita (PC) is a skin disorder resulting from mutations in keratin (K) proteins including K6a, K6b, K16, and K17. One of the major symptoms is painful plantar keratoderma....
9.
Hegde V, Hickerson R, Nainamalai S, Campbell P, Smith F, McLean W, et al.
J Control Release
. 2014 Dec;
196:355-62.
PMID: 25449884
Therapeutics based on short interfering RNAs (siRNAs), which act by inhibiting the expression of target transcripts, represent a novel class of potent and highly specific next-generation treatments for human skin...
10.
Lessard J, Pina-Paz S, Rotty J, Hickerson R, Kaspar R, Balmain A, et al.
Proc Natl Acad Sci U S A
. 2013 Nov;
110(48):19537-42.
PMID: 24218583
Mutations in the type I keratin 16 (Krt16) and its partner type II keratin 6 (Krt6a, Krt6b) cause pachyonychia congenita (PC), a disorder typified by dystrophic nails, painful hyperkeratotic calluses...