Robert R Stickels
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Explore the profile of Robert R Stickels including associated specialties, affiliations and a list of published articles.
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9
Citations
1539
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Recent Articles
1.
Ngo W, Peukes J, Baldwin A, Xue Z, Hwang S, Stickels R, et al.
Proc Natl Acad Sci U S A
. 2025 Jan;
122(1):e2413519121.
PMID: 39793042
The widespread application of genome editing to treat and cure disease requires the delivery of genome editors into the nucleus of target cells. Enveloped delivery vehicles (EDVs) are engineered virally...
2.
Abay T, Stickels R, Takizawa M, Nalbant B, Hsieh Y, Hwang S, et al.
Nat Genet
. 2025 Jan;
57(2):451-460.
PMID: 39779958
Single-cell genomics technologies have accelerated our understanding of cell-state heterogeneity in diverse contexts. Although single-cell RNA sequencing identifies rare populations that express specific marker transcript combinations, traditional flow sorting requires...
3.
Jones M, Sun D, Min K, Colgan W, Tian L, Weir J, et al.
bioRxiv
. 2024 Nov;
PMID: 39484491
Tumor progression is driven by dynamic interactions between cancer cells and their surrounding microenvironment. Investigating the spatiotemporal evolution of tumors can provide crucial insights into how intrinsic changes within cancer...
4.
Ngo W, Peukes J, Baldwin A, Xue Z, Hwang S, Stickels R, et al.
bioRxiv
. 2024 Aug;
PMID: 39091760
The widespread application of genome editing to treat or even cure disease requires the delivery of genome editors into the nucleus of target cells. Enveloped Delivery Vehicles (EDVs) are engineered...
5.
Abay T, Stickels R, Takizawa M, Nalbant B, Hsieh Y, Hwang S, et al.
bioRxiv
. 2024 Apr;
PMID: 38586040
Single-cell genomics technologies have accelerated our understanding of cell-state heterogeneity in diverse contexts. Although single-cell RNA sequencing (scRNA-seq) identifies many rare populations of interest that express specific marker transcript combinations,...
6.
Lareau C, Yin Y, Maurer K, Sandor K, Daniel B, Yagnik G, et al.
Nature
. 2023 Nov;
623(7987):608-615.
PMID: 37938768
Cell therapies have yielded durable clinical benefits for patients with cancer, but the risks associated with the development of therapies from manipulated human cells are understudied. For example, we lack...
7.
Marshall J, Noel T, Wang Q, Chen H, Murray E, Subramanian A, et al.
iScience
. 2022 Apr;
25(4):104097.
PMID: 35372810
High-resolution spatial transcriptomics enables mapping of RNA expression directly from intact tissue sections; however, its utility for the elucidation of disease processes and therapeutically actionable pathways remains unexplored. We applied...
8.
Di Bella D, Habibi E, Stickels R, Scalia G, Brown J, Yadollahpour P, et al.
Nature
. 2021 Aug;
596(7873):E11.
PMID: 34341543
No abstract available.
9.
Di Bella D, Habibi E, Stickels R, Scalia G, Brown J, Yadollahpour P, et al.
Nature
. 2021 Jun;
595(7868):554-559.
PMID: 34163074
The mammalian cerebral cortex has an unparalleled diversity of cell types, which are generated during development through a series of temporally orchestrated events that are under tight evolutionary constraint and...
10.
Stickels R, Murray E, Kumar P, Li J, Marshall J, Di Bella D, et al.
Nat Biotechnol
. 2020 Dec;
39(3):313-319.
PMID: 33288904
Measurement of the location of molecules in tissues is essential for understanding tissue formation and function. Previously, we developed Slide-seq, a technology that enables transcriptome-wide detection of RNAs with a...