Robert R Langley
Overview
Explore the profile of Robert R Langley including associated specialties, affiliations and a list of published articles.
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Articles
55
Citations
3048
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Recent Articles
1.
Moreno-Smith M, Halder J, Meltzer P, Gonda T, Mangala L, Rupaimoole R, et al.
J Clin Invest
. 2021 Apr;
131(7).
PMID: 33792569
No abstract available.
2.
Moreno-Smith M, Halder J, Meltzer P, Gonda T, Mangala L, Rupaimoole R, et al.
J Clin Invest
. 2018 May;
128(7):3199.
PMID: 29809169
No abstract available.
3.
Cascone T, Xu L, Lin H, Liu W, Tran H, Liu Y, et al.
Clin Cancer Res
. 2017 Jun;
23(18):5489-5501.
PMID: 28559461
Resistance to VEGFR inhibitors is a major obstacle in the treatment of non-small cell lung cancer (NSCLC). We investigated the cellular mechanisms mediating resistance of NSCLCs to VEGFR tyrosine kinase...
4.
Lee H, Hanibuchi M, Kim S, Yu H, Kim M, He J, et al.
Neuro Oncol
. 2016 Mar;
18(4):486-96.
PMID: 26995790
Background: We recently demonstrated that brain endothelial cells and astrocytes protect cancer cells from chemotherapy through an endothelin-dependent signaling mechanism. Here, we evaluated the efficacy of macitentan, a dual endothelin...
5.
Previs R, Armaiz-Pena G, Lin Y, Davis A, Pradeep S, Dalton H, et al.
Mol Cancer Ther
. 2015 Oct;
14(12):2677-86.
PMID: 26516159
There is growing recognition of the important role of metronomic chemotherapy in cancer treatment. On the basis of their unique antiangiogenic effects, we tested the efficacy of nab-paclitaxel, which stimulates...
6.
Kim S, Lee H, Kim M, Choi H, He J, Wu Q, et al.
Clin Cancer Res
. 2015 Jun;
21(20):4630-41.
PMID: 26106074
Purpose: The objective of the study was to determine whether astrocytes and brain endothelial cells protect glioma cells from temozolomide through an endothelin-dependent signaling mechanism and to examine the therapeutic...
7.
Kim S, Kim S, Langley R, Fidler I
Int J Oncol
. 2015 Mar;
46(5):2067-75.
PMID: 25776572
We investigated how varying the composition of cell culture formulations and growing cancer cells at different densities might affect tumor cell genotype. Specifically, we compared gene expression profiles generated by...
8.
Yu H, Lee H, Yun S, Lee S, Langley R, Yoon Y, et al.
Transl Oncol
. 2014 Sep;
7(3):368-76.
PMID: 25180060
Introduction: The present study compared the effect of combination therapy using human apolipoprotein(a) kringle V (rhLK8) to conventional chemotherapy with paclitaxel for human ovarian carcinoma producing high or low levels...
9.
Kim S, Choi H, Lee H, He J, Wu Q, Langley R, et al.
Neuro Oncol
. 2014 Jul;
16(12):1585-98.
PMID: 25008093
Background: Recent evidence suggests that astrocytes protect cancer cells from chemotherapy by stimulating upregulation of anti-apoptotic genes in those cells. We investigated the possibility that activation of the endothelin axis...
10.
Wan G, Zhang X, Langley R, Liu Y, Hu X, Han C, et al.
Cell Rep
. 2013 Jun;
3(6):2100-12.
PMID: 23791529
Expression of microRNAs (miRNAs) involves transcription of miRNA genes and maturation of the primary transcripts. Recent studies have shown that posttranscriptional processing of primary and precursor miRNAs is induced after...