Robert R Haines
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Explore the profile of Robert R Haines including associated specialties, affiliations and a list of published articles.
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6
Citations
477
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Recent Articles
1.
Haines R, Scharer C, Lobby J, Boss J
J Immunol
. 2019 Sep;
203(7):1867-1881.
PMID: 31492745
Marginal zone B cells (MZB) are a mature B cell subset that rapidly respond to blood-borne pathogens. Although the transcriptional changes that occur throughout MZB development are known, the corresponding...
2.
Haines R, Barwick B, Scharer C, Majumder P, Randall T, Boss J
J Immunol
. 2018 Sep;
201(9):2799-2811.
PMID: 30232138
B cells undergo epigenetic remodeling as they differentiate into Ab-secreting cells (ASC). LSD1 is a histone demethylase known to decommission active enhancers and cooperate with the ASC master regulatory transcription...
3.
Barwick B, Scharer C, Martinez R, Price M, Wein A, Haines R, et al.
Nat Commun
. 2018 May;
9(1):1900.
PMID: 29765016
B cells provide humoral immunity by differentiating into antibody-secreting plasma cells, a process that requires cellular division and is linked to DNA hypomethylation. Conversely, little is known about how de...
4.
Guo M, Price M, Patterson D, Barwick B, Haines R, Kania A, et al.
J Immunol
. 2017 Dec;
200(3):1039-1052.
PMID: 29288200
Epigenetic remodeling is required during B cell differentiation. However, little is known about the direct functions of epigenetic enzymes in Ab-secreting cells (ASC) in vivo. In this study, we examined...
5.
Scharer C, Blalock E, Barwick B, Haines R, Wei C, Sanz I, et al.
Sci Rep
. 2016 Jun;
6:27030.
PMID: 27249108
Biobanking is a widespread practice for storing biological samples for future studies ranging from genotyping to RNA analysis. However, methods that probe the status of the epigenome are lacking. Here,...
6.
Doroghazi J, Albright J, Goering A, Ju K, Haines R, Tchalukov K, et al.
Nat Chem Biol
. 2014 Sep;
10(11):963-8.
PMID: 25262415
Actinobacteria encode a wealth of natural product biosynthetic gene clusters, whose systematic study is complicated by numerous repetitive motifs. By combining several metrics, we developed a method for the global...