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Troy D Randall

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Articles 138
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Recent Articles
1.
Wiggins K, Williams M, Hicks S, Padilla-Quirarte H, Akther J, Randall T, et al.
J Immunol . 2025 Mar; PMID: 40073167
Antigen-experienced memory B-cells (MBC) are endowed with enhanced functional properties compared to naïve B cells and play an important role in the humoral response. However, the epigenetic enzymes and programs...
2.
Molina P, Edell C, Dunaway L, Kellum C, Muir R, Jennings M, et al.
Function (Oxf) . 2025 Jan; PMID: 39779302
Excess dietary salt and salt-sensitivity contribute to cardiovascular disease. Distinct T cell phenotypic responses to high salt and hypertension as well as influences from environmental cues are not well understood....
3.
Peel J, Owiredu E, Rosenberg A, Silva-Sanchez A, Randall T, Kearney J, et al.
J Immunol . 2024 Oct; 213(12):1771-1786. PMID: 39451043
The prototypic IFN-inducible transcription factor, IRF1, not only controls inflammatory gene expression but also regulates T cell and macrophage fate specification and function. Using bone marrow chimeras (80% B6.129S2-Ighmtm1Cgn/J [µMT]...
4.
Meza-Perez S, Liu M, Silva-Sanchez A, Morrow C, Eipers P, Lefkowitz E, et al.
Cell Host Microbe . 2024 Jun; 32(7):1177-1191.e7. PMID: 38942027
Gut microbiota influence anti-tumor immunity, often by producing immune-modulating metabolites. However, microbes consume a variety of metabolites that may also impact host immune responses. We show that tumors grow unchecked...
5.
Randall T, Meza-Perez S
Immunol Rev . 2024 May; 324(1):4-10. PMID: 38733141
Well known functions of adipose tissue include energy storage, regulation of thermogenesis, and glucose homeostasis-each of which are associated with the metabolic functions of fat. However, adipose tissues also have...
6.
Arroyo-Diaz N, Bachus H, Papillion A, Randall T, Akther J, Rosenberg A, et al.
Immunity . 2023 Sep; 56(10):2358-2372.e5. PMID: 37699392
Lung-resident memory B cells (lung-BRMs) differentiate into plasma cells after reinfection, providing enhanced pulmonary protection. Here, we investigated the determinants of lung-BRM differentiation upon influenza infection. Kinetic analyses revealed that...
7.
Curtiss M, Rosenberg A, Scharer C, Mousseau B, Benavides N, Bradley J, et al.
Front Immunol . 2023 Aug; 14:1158493. PMID: 37575256
Introduction: Data from patient cohorts and mouse models of atopic dermatitis, food allergy and asthma strongly support a role for chitinase-3-like-1 protein (CHI3L1) in allergic disease. Methods: To address whether...
8.
Silva-Sanchez A, Meza-Perez S, Liu M, Stone S, Flores-Romo L, Ubil E, et al.
Sci Immunol . 2023 Jun; 8(84):eadc9081. PMID: 37327322
Multiple mechanisms restrain inflammation in neonates, most likely to prevent tissue damage caused by overly robust immune responses against newly encountered pathogens. Here, we identify a population of pulmonary dendritic...
9.
Killian J, King R, Lucander A, Kizziah J, Fucile C, Diaz-Avalos R, et al.
bioRxiv . 2023 Apr; PMID: 37034637
Donor-specific antibody (DSA) responses against human leukocyte antigen (HLA) proteins mismatched between kidney transplant donors and recipients cause allograft loss. The rules governing the immunogenicity of non-self donor HLA are...
10.
Nellore A, Zumaquero E, Scharer C, Fucile C, Tipton C, King R, et al.
Immunity . 2023 Mar; 56(4):847-863.e8. PMID: 36958335
Seasonal influenza vaccination elicits hemagglutinin (HA)-specific memory B (Bmem) cells, and although multiple Bmem cell populations have been characterized, considerable heterogeneity exists. We found that HA-specific human Bmem cells differed...