Robert Pawlak
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Explore the profile of Robert Pawlak including associated specialties, affiliations and a list of published articles.
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29
Citations
1051
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Recent Articles
1.
Belal M, Mucha M, Monteil A, Winyard P, Pawlak R, Walker J, et al.
J Physiol
. 2024 Dec;
603(2):301-317.
PMID: 39620829
The pituitary gland produces and secretes a variety of hormones that are essential to life, such as for the regulation of growth and development, metabolism, reproduction, and the stress response....
2.
Mucha M, Skrzypiec A, Kolenchery J, Brambilla V, Patel S, Labrador-Ramos A, et al.
Nat Commun
. 2023 May;
14(1):2134.
PMID: 37185241
Severe psychological trauma triggers genetic, biochemical and morphological changes in amygdala neurons, which underpin the development of stress-induced behavioural abnormalities, such as high levels of anxiety. miRNAs are small, non-coding...
3.
Koper-Lenkiewicz O, Milewska A, Kaminska J, Sawicki K, Chrzanowski R, Zinczuk J, et al.
Ann Med
. 2021 Oct;
53(1):1710-1721.
PMID: 34601991
Introduction: Taking into account the possibility of myelin-associated proteins having a role in brain tumour development, the study aimed to evaluate the diagnostic usefulness of myelin-associated proteins (Nogo-A, MAG, OMgp)...
4.
Zhang J, Bhuiyan M, Zhang T, Karimy J, Wu Z, Fiesler V, et al.
Nat Commun
. 2020 Jan;
11(1):78.
PMID: 31911626
The SLC12A cation-Cl cotransporters (CCC), including NKCC1 and the KCCs, are important determinants of brain ionic homeostasis. SPAK kinase (STK39) is the CCC master regulator, which stimulates NKCC1 ionic influx...
5.
Morales-AcuNa F, Ratcliffe B, Harrison C, Crowe S, Bockover E, Pawlak R, et al.
Eur J Appl Physiol
. 2019 Jan;
119(4):901-911.
PMID: 30659353
Purpose: Non-invasive central blood pressure assessed during exercise may provide better cardiovascular prognostic than measurements taken at rest. Radial tonometry is the only technique validated to perform this type of...
6.
Ratcliffe B, Pawlak R, Morales F, Harrison C, Gurovich A
Clin Hypertens
. 2017 Aug;
23:17.
PMID: 28852570
Background: Flow Mediated Dilation (FMD) has immense potential to become a clinical, non-invasive biomarker of endothelial function and nitric oxide bioavailability, which regulate vasomotor activity. Unfortunately, FMD analysis techniques could...
7.
Bradley S, Bourgognon J, Sanger H, Verity N, Mogg A, White D, et al.
J Clin Invest
. 2016 Dec;
127(2):487-499.
PMID: 27991860
The current frontline symptomatic treatment for Alzheimer's disease (AD) is whole-body upregulation of cholinergic transmission via inhibition of acetylcholinesterase. This approach leads to profound dose-related adverse effects. An alternative strategy...
8.
Harlalka G, McEntagart M, Gupta N, Skrzypiec A, Mucha M, Chioza B, et al.
Hum Mutat
. 2016 Aug;
37(11):1157-1161.
PMID: 27492651
Hereditary spastic paraplegias (HSPs) are genetically and clinically heterogeneous axonopathies primarily affecting upper motor neurons and, in complex forms, additional neurons. Here, we report two families with distinct recessive mutations...
9.
Hall M, Magalska A, Malinowska M, Ruszczycki B, Czaban I, Patel S, et al.
Brain Struct Funct
. 2015 May;
221(5):2511-25.
PMID: 25956166
PML is a tumor suppressor protein involved in the pathogenesis of promyelocytic leukemia. In non-neuronal cells, PML is a principal component of characteristic nuclear bodies. In the brain, PML has...
10.
Tsilibary E, Tzinia A, Radenovic L, Stamenkovic V, Lebitko T, Mucha M, et al.
Prog Brain Res
. 2014 Nov;
214:135-57.
PMID: 25410356
Recent studies implicate extracellular proteases in synaptic plasticity, learning, and memory. The data are especially strong for such serine proteases as thrombin, tissue plasminogen activator, neurotrypsin, and neuropsin as well...