Robert L Strausberg
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Explore the profile of Robert L Strausberg including associated specialties, affiliations and a list of published articles.
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67
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13022
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Recent Articles
1.
Timosenko E, Ghadbane H, Silk J, Shepherd D, Gileadi U, Howson L, et al.
Cancer Res
. 2016 Sep;
76(21):6193-6204.
PMID: 27651314
Tryptophan degradation is an immune escape strategy shared by many tumors. However, cancer cells' compensatory mechanisms remain unclear. We demonstrate here that a shortage of tryptophan caused by expression of...
2.
Tie J, Wang Y, Tomasetti C, Li L, Springer S, Kinde I, et al.
Sci Transl Med
. 2016 Jul;
8(346):346ra92.
PMID: 27384348
Detection of circulating tumor DNA (ctDNA) after resection of stage II colon cancer may identify patients at the highest risk of recurrence and help inform adjuvant treatment decisions. We used...
3.
Yao J, Caballero O, Huang Y, Lin C, Rimoldi D, Behren A, et al.
Cancer Immunol Res
. 2016 Apr;
4(6):552-61.
PMID: 27045022
Melanoma is one of the major cancer types for which new immune-based cancer treatments have achieved promising results. However, anti-PD-1 and anti-CTLA-4 therapies are effective only in some patients. Hence,...
4.
Jorissen R, Christie M, Mouradov D, Sakthianandeswaren A, Li S, Love C, et al.
Br J Cancer
. 2015 Aug;
113(6):979-88.
PMID: 26305864
Background: APC mutations (APC-mt) occur in ∼70% of colorectal cancers (CRCs), but their relationship to prognosis is unclear. Methods: APC prognostic value was evaluated in 746 stage I-IV CRC patients,...
5.
Donnard E, Asprino P, Correa B, Bettoni F, Koyama F, Navarro F, et al.
Oncotarget
. 2014 Sep;
5(19):9199-213.
PMID: 25193853
We carried out a mutational analysis of 3,594 genes coding for cell surface proteins (Surfaceome) in 23 colorectal cancer cell lines, searching for new altered pathways, druggable mutations and mutated...
6.
Baia G, Caballero O, Ho J, Zhao Q, Cohen T, Binder Z, et al.
Cancer Immunol Res
. 2014 Apr;
1(5):296-302.
PMID: 24777967
Meningiomas are the most common primary intracranial tumors. Surgical resection remains the treatment of choice for these tumors. However, a significant number of tumors are not surgically accessible, recur, or...
7.
Yao J, Caballero O, Yung W, Weinstein J, Riggins G, Strausberg R, et al.
Cancer Immunol Res
. 2014 Apr;
2(4):371-9.
PMID: 24764584
Cancer-testis (CT) antigens are potential targets for cancer immunotherapy because of their restricted expression in immune-privileged germ cells and various malignancies. Current application of CT-based immunotherapy has been focused on...
8.
Mouradov D, Sloggett C, Jorissen R, Love C, Li S, Burgess A, et al.
Cancer Res
. 2014 Apr;
74(12):3238-47.
PMID: 24755471
Human colorectal cancer cell lines are used widely to investigate tumor biology, experimental therapy, and biomarkers. However, to what extent these established cell lines represent and maintain the genetic diversity...
9.
Day F, Jorissen R, Lipton L, Mouradov D, Sakthianandeswaren A, Christie M, et al.
Clin Cancer Res
. 2013 May;
19(12):3285-96.
PMID: 23633456
Purpose: PIK3CA and PTEN mutations are prevalent in colorectal cancer and potential markers of response to mitogen-activated protein/extracellular signal-regulated kinase inhibitors and anti-EGF receptor antibody therapy. Relationships between phosphoinositide 3-kinase...
10.
Zhao Q, Caballero O, Davis I, Jonasch E, Tamboli P, Yung W, et al.
Clin Cancer Res
. 2013 Feb;
19(9):2460-72.
PMID: 23444225
Purpose: We aim to identify tumor-specific alternative splicing events having potential applications in the early detection, diagnosis, prognosis, and therapy for cancers. Experimental Design: We analyzed RNA-seq data on 470...