Robert J Schneider
Overview
Explore the profile of Robert J Schneider including associated specialties, affiliations and a list of published articles.
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Articles
133
Citations
6028
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Recent Articles
1.
Mohamed M, Schneider R
QJM
. 2024 Oct;
117(12):831-835.
PMID: 39437012
Inflammatory breast cancer (IBC) is the most aggressive and lethal phenotype form of breast cancer, which afflicts young women at high incidence in North Africa compared to other continents of...
2.
Cruz-Collazo A, Katsara O, Grafals-Ruiz N, Colon Gonzalez J, Dorta-Estremera S, Carlo V, et al.
Mol Cancer Ther
. 2024 Aug;
23(11):1613-1625.
PMID: 39087451
Triple negative breast cancer (TNBC) represents a therapeutic challenge in which standard chemotherapy is limited to paclitaxel. MBQ167, a clinical stage small molecule inhibitor that targets Rac and Cdc42, inhibits...
3.
Mahe M, Rios-Fuller T, Katsara O, Schneider R
NAR Cancer
. 2024 Jun;
6(2):zcae026.
PMID: 38828390
The now well described canonical mRNA translation initiation mechanism of mG 'cap' recognition by cap-binding protein eIF4E and assembly of the canonical pre-initiation complex consisting of scaffolding protein eIF4G and...
4.
Mahe M, Rios-Fuller T, Karolin A, Schneider R
Front Oncol
. 2023 Aug;
13:1230934.
PMID: 37601653
Inherited metabolic disorders arise from mutations in genes involved in the biogenesis, assembly, or activity of metabolic enzymes, leading to enzymatic deficiency and severe metabolic impairments. Metabolic enzymes are essential...
5.
Alard A, Katsara O, Rios-Fuller T, de la Parra C, Ozerdem U, Ernlund A, et al.
Cell Rep
. 2023 Jun;
42(6):112646.
PMID: 37314929
Cancer cell plasticity enables cell survival in harsh physiological environments and fate transitions such as the epithelial-to-mesenchymal transition (EMT) that underlies invasion and metastasis. Using genome-wide transcriptomic and translatomic studies,...
6.
Gupta M, Walters B, Katsara O, Granados Blanco K, Geter P, Schneider R
Proc Natl Acad Sci U S A
. 2023 Apr;
120(15):e2207898120.
PMID: 37014850
Breast cancer (BC) metastasis involves cancer stem cells (CSCs) and their regulation by micro-RNAs (miRs), but miR targeting of the translation machinery in CSCs is poorly explored. We therefore screened...
7.
Canfran-Duque A, Rotllan N, Zhang X, Andres-Blasco I, Thompson B, Sun J, et al.
Circulation
. 2022 Nov;
147(5):388-408.
PMID: 36416142
Background: Cross-talk between sterol metabolism and inflammatory pathways has been demonstrated to significantly affect the development of atherosclerosis. Cholesterol biosynthetic intermediates and derivatives are increasingly recognized as key immune regulators...
8.
Sadic M, Schneider W, Katsara O, Medina G, Fisher A, Mogulothu A, et al.
EMBO Rep
. 2022 Oct;
23(12):e55218.
PMID: 36256515
Co-opting host cell protein synthesis is a hallmark of many virus infections. In response, certain host defense proteins limit mRNA translation globally, albeit at the cost of the host cell's...
9.
Mohamed H, El-Sharkawy A, El-Shinawi M, Schneider R, Mohamed M
Front Oncol
. 2022 Jul;
12:899622.
PMID: 35847899
Inflammatory breast cancer (IBC) is a highly aggressive phenotype of breast cancer that is characterized by a high incidence early metastasis. We previously reported a significant association of human cytomegalovirus...
10.
Patel P, Perez-Baos S, Walters B, Orlen M, Volkova A, Ruggles K, et al.
Sci Adv
. 2022 Jun;
8(25):eabo1782.
PMID: 35749506
Little is known regarding T cell translational regulation. We demonstrate that T follicular helper (TFH) cells use a previously unknown mechanism of selective messenger RNA (mRNA) translation for their differentiation,...