Robert J Munroe
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Explore the profile of Robert J Munroe including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
946
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0
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Recent Articles
1.
Cheng C, Hwang C, Corney D, Flesken-Nikitin A, Jiang L, Oner G, et al.
Cell Rep
. 2014 Mar;
6(6):1000-1007.
PMID: 24630988
The miR-34 family was originally found to be a direct target of p53 and is a group of putative tumor suppressors. Surprisingly, mice lacking all mir-34 genes show no increase...
2.
Harris T, Schimenti K, Munroe R, Schimenti J
G3 (Bethesda)
. 2013 Dec;
4(2):367-72.
PMID: 24362311
Spermiogenesis in mammals is the process by which the newly formed products of meiosis, haploid spermatids, undergo a dramatic morphological transformation from round cells into flagellated spermatozoa. The underlying genetic...
3.
Min I, Waterfall J, Core L, Munroe R, Schimenti J, Lis J
Genes Dev
. 2011 Apr;
25(7):742-54.
PMID: 21460038
Transitions between pluripotent stem cells and differentiated cells are executed by key transcription regulators. Comparative measurements of RNA polymerase distribution over the genome's primary transcription units in different cell states...
4.
Ching Y, Munroe R, Moran J, Barker A, Mauceli E, Fennell T, et al.
BMC Genet
. 2010 Dec;
11:106.
PMID: 21118569
Background: Forward genetic screens in mice provide an unbiased means to identify genes and other functional genetic elements in the genome. Previously, a large scale ENU mutagenesis screen was conducted...
5.
Mu W, Munroe R, Barker A, Schimenti J
Dev Biol
. 2010 Sep;
347(2):279-88.
PMID: 20813103
PDCD2 is a conserved eukaryotic protein implicated in cell cycle regulation by virtue of its interactions with HCFC1 and the NCOR1/SIN3A corepressor complex. Pdcd2 transcripts are enriched in ES cells...
6.
Francisco A, Singh R, Li S, Vani A, Yang L, Munroe R, et al.
J Biol Chem
. 2010 Mar;
285(18):13694-703.
PMID: 20197277
Stress in the endoplasmic reticulum (ER) plays an important causal role in the pathogenesis of several chronic diseases such as Alzheimer, Parkinson, and diabetes mellitus. Insight into the genetic determinants...
7.
Li S, Francisco A, Munroe R, Schimenti J, Long Q
BMC Dev Biol
. 2010 Feb;
10:19.
PMID: 20170518
Background: The vertebrate pancreas contains islet, acinar and ductal cells. These cells derive from a transient pool of multipotent pancreatic progenitors during embryonic development. Insight into the genetic determinants regulating...
8.
Munroe R, Prabhu V, Acland G, Johnson K, Harris B, OBrien T, et al.
BMC Dev Biol
. 2009 Apr;
9:27.
PMID: 19379485
Background: The H6 homeobox genes Hmx1, Hmx2, and Hmx3 (also known as Nkx5-3; Nkx5-2 and Nkx5-1, respectively), compose a family within the NKL subclass of the ANTP class of homeobox...
9.
Shima N, Alcaraz A, Liachko I, Buske T, Andrews C, Munroe R, et al.
Nat Genet
. 2006 Dec;
39(1):93-8.
PMID: 17143284
Mcm4 (minichromosome maintenance-deficient 4 homolog) encodes a subunit of the MCM2-7 complex (also known as MCM2-MCM7), the replication licensing factor and presumptive replicative helicase. Here, we report that the mouse...
10.
Reinholdt L, Munroe R, Kamdar S, Schimenti J
Mech Dev
. 2006 Jul;
123(7):559-69.
PMID: 16822657
Germ cell depletion 2 (gcd2) is a chemically induced recessive mutation that causes infertility in male and female mice. The infertility is caused by germ cell depletion as early as...