Robert Heuschkel
Overview
Explore the profile of Robert Heuschkel including associated specialties, affiliations and a list of published articles.
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44
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1202
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Recent Articles
1.
Dennison T, Edgar R, Payne F, Nayak K, Ross A, Cenier A, et al.
Gut
. 2024 Jun;
73(9):1464-1477.
PMID: 38857990
Objective: Epigenetic mechanisms, including DNA methylation (DNAm), have been proposed to play a key role in Crohn's disease (CD) pathogenesis. However, the specific cell types and pathways affected as well...
2.
Wang Y, Robinson P, Coorens T, Moore L, Lee-Six H, Noorani A, et al.
Nat Genet
. 2023 Jan;
55(2):246-254.
PMID: 36702998
APOBEC mutational signatures SBS2 and SBS13 are common in many human cancer types. However, there is an incomplete understanding of its stimulus, when it occurs in the progression from normal...
3.
Culture-Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids
Edgar R, Perrone F, Foster A, Payne F, Lewis S, Nayak K, et al.
Cell Mol Gastroenterol Hepatol
. 2022 Aug;
14(6):1295-1310.
PMID: 36038072
Background & Aims: Human intestinal epithelial organoids (IEOs) are a powerful tool to model major aspects of intestinal development, health, and diseases because patient-derived cultures retain many features found in ...
4.
Serra E, Schwerd T, Moutsianas L, Cavounidis A, Fachal L, Pandey S, et al.
Nat Commun
. 2022 Jun;
13(1):3576.
PMID: 35732629
No abstract available.
5.
Hensel K, Kyrana E, Hadzic N, Mann J, Mieli-Vergani G, Gasparetto M, et al.
J Pediatr
. 2021 Jul;
238:50-56.e3.
PMID: 34303727
Objective: To describe the characteristics and clinical course of children and young persons with inflammatory bowel disease (IBD) and sclerosing cholangitis (SC). Study Design: Retrospective analysis of clinical characteristics, management,...
6.
Zilbauer M, Heuschkel R
J Crohns Colitis
. 2021 Jul;
16(1):162-165.
PMID: 34240137
Inflammatory bowel diseases [IBD] such as Crohn's disease [CD] and ulcerative colitis [UC] are complex conditions presenting with a wide range of phenotypes. Given major variation in disease severity and...
7.
Zilbauer M, Heuschkel R
Gastroenterology
. 2021 Jan;
160(6):2211-2212.
PMID: 33508288
No abstract available.
8.
Elmentaite R, Ross A, Roberts K, James K, Ortmann D, Gomes T, et al.
Dev Cell
. 2020 Dec;
55(6):771-783.e5.
PMID: 33290721
Human gut development requires the orchestrated interaction of differentiating cell types. Here, we generate an in-depth single-cell map of the developing human intestine at 6-10 weeks post-conception. Our analysis reveals...
9.
Wong E, Heuschkel R, Lindsay C, Benson S, Zilbauer M
Eur J Pediatr
. 2020 Oct;
180(4):1307-1312.
PMID: 33067712
Clinical psychology intervention in paediatric gastroenterology is vital given the biopsychosocial aetiology of paediatric functional gastrointestinal disorders, and the psychological impact of chronic conditions. The aim was to assess the...
10.
Gasparetto M, Payne F, Nayak K, Kraiczy J, Glemas C, Philip-McKenzie Y, et al.
Gastroenterology
. 2020 Aug;
160(1):232-244.e7.
PMID: 32814113
Background & Aims: Gene expression patterns of CD8 T cells have been reported to correlate with clinical outcomes of adults with inflammatory bowel diseases (IBD). We aimed to validate these...