Alan D Phillips
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Explore the profile of Alan D Phillips including associated specialties, affiliations and a list of published articles.
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44
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1352
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Recent Articles
1.
Salvestrini C, Lucas M, Lionetti P, Torrente F, James S, Phillips A, et al.
PLoS One
. 2014 Sep;
9(9):e106005.
PMID: 25198673
Background: We studied the expression of sulphated glycosaminoglycans (GAGs) in coeliac disease (CD) mucosa, as they are critical determinants of tissue volume, which increases in active disease. We also examined...
2.
Tran S, Billoud L, Lewis S, Phillips A, Schuller S
Cell Microbiol
. 2014 Mar;
16(8):1255-66.
PMID: 24612002
Haemolytic uraemic syndrome caused by Shiga toxin-producing E. coli (STEC) is dependent on release of Shiga toxins (Stxs) during intestinal infection and subsequent absorption into the bloodstream. An understanding of...
3.
Edwards L, Bajaj-Elliott M, Klein N, Murch S, Phillips A
PLoS One
. 2011 Nov;
6(10):e27030.
PMID: 22046438
Background: Enteropathogenic (EPEC) and Enteroaggregative (EAEC) E. coli have similar, but distinct clinical symptoms and modes of pathogenesis. Nevertheless when they infect the gastrointestinal tract, it is thought that their...
4.
Edwards L, ONeill C, Furman M, Hicks S, Torrente F, Perez-Machado M, et al.
Inflamm Bowel Dis
. 2011 Sep;
18(4):624-40.
PMID: 21887731
Background: Enterotoxin-producing Staphylococcus aureus may cause severe inflammatory intestinal disease, particularly in infants or immunodeficient or elderly patients. They are also recognized to be associated with sudden infant death syndrome....
5.
Lechner S, Ruemmele F, Zankl A, Lausch E, Huber W, Mihatsch W, et al.
J Pediatr Gastroenterol Nutr
. 2011 Jun;
53(1):48-54.
PMID: 21694535
Objectives: Autosomal recessive, congenital chloride diarrhea (CLD) is a form of persistent secretory diarrhea, presenting with polyhydramnios and intractable diarrhea from birth. CLD is caused by mutations in the SLC26A3...
6.
Zilbauer M, Jenke A, Wenzel G, Postberg J, Heusch A, Phillips A, et al.
PLoS One
. 2010 Nov;
5(10):e15389.
PMID: 21042595
Background: Human beta-defensins (hBDs) are antimicrobial peptides known to play a major role in intestinal innate host defence. Altered mucosal expression of hBDs has been suggested to be implicated in...
7.
Newton H, Pearson J, Badea L, Kelly M, Lucas M, Holloway G, et al.
PLoS Pathog
. 2010 May;
6(5):e1000898.
PMID: 20485572
Many bacterial pathogens utilize a type III secretion system to deliver multiple effector proteins into host cells. Here we found that the type III effectors, NleE from enteropathogenic E. coli...
8.
Schuller S, Phillips A
Environ Microbiol
. 2010 Apr;
12(9):2426-35.
PMID: 20406285
Advances in the understanding of the pathogenesis of enterohaemorrhagic Escherichia coli (EHEC) have greatly benefited from the use of human epithelial cell lines under aerobic conditions. However, in the target...
9.
Crepin V, Girard F, Schuller S, Phillips A, Mousnier A, Frankel G
Mol Microbiol
. 2009 Nov;
75(2):308-23.
PMID: 19889090
Attaching and effacing (A/E) lesions and actin polymerization, the hallmark of enteropathogenic Escherichia coli (EPEC), enterohemorrhagic E. coli (EHEC) and Citrobacter rodentium (CR) infections, are dependent on the effector Tir....
10.
Saldana Z, Erdem A, Schuller S, Okeke I, Lucas M, Sivananthan A, et al.
J Bacteriol
. 2009 Feb;
191(11):3451-61.
PMID: 19218393
Although the bundle-forming pilus (BFP) of enteropathogenic Escherichia coli (EPEC) mediates microcolony formation on epithelial cells, the adherence of BFP-deficient mutants is significantly abrogated, but the mutants are still adherent...