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Robert H Costa

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Articles 56
Citations 3930
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31.
Krupczak-Hollis K, Wang X, Kalinichenko V, Gusarova G, Wang I, Dennewitz M, et al.
Dev Biol . 2004 Nov; 276(1):74-88. PMID: 15531365
Conditional deletion of the mouse Forkhead Box (Fox) m1b targeted allele in adult hepatocytes (Foxm1, previously called HFH-11B, Trident, Win, or MPP2) demonstrated that the Foxm1b transcription factor is essential...
32.
Wang M, Tan Y, Costa R, Holterman A
Hepatology . 2004 Sep; 40(3):600-8. PMID: 15349898
Disruption of the enterohepatic bile acid circulation during biliary tract obstruction leads to profound perturbation of the cholesterol and bile acid metabolic pathways. Several families of nuclear receptor proteins have...
33.
Rausa 3rd F, Hughes D, Costa R
J Biol Chem . 2004 Aug; 279(41):43070-6. PMID: 15304484
We previously demonstrated that the formation of complexes between the DNA binding domains of the hepatocyte nuclear factor 6 (HNF6) and Forkhead Box a2 (Foxa2) transcription factors resulted in synergistic...
34.
Sheng W, Yan H, Rausa 3rd F, Costa R, Liao X
J Biol Chem . 2004 Jun; 279(32):33928-36. PMID: 15169783
Hepatocyte nuclear factor 6 (HNF-6) belongs to the family of One Cut transcription factors (also known as OC-1) and is essential for the development of the mouse pancreas, gall bladder,...
35.
Kalinichenko V, Major M, Wang X, Petrovic V, Kuechle J, Yoder H, et al.
Genes Dev . 2004 Apr; 18(7):830-50. PMID: 15082532
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide. Here, we provide evidence that the Forkhead Box (Fox) m1b (Foxm1b or Foxm1) transcription factor is essential for the...
36.
Major M, Lepe R, Costa R
Mol Cell Biol . 2004 Mar; 24(7):2649-61. PMID: 15024056
Previous liver regeneration studies demonstrated that the mouse forkhead box M1B (FoxM1B) transcription factor regulates hepatocyte proliferation through expression of cell cycle genes that stimulate cyclin-dependent kinase 2 (Cdk2) and...
37.
Wang X, Bhattacharyya D, Dennewitz M, Kalinichenko V, Zhou Y, Lepe R, et al.
Gene Expr . 2003 Dec; 11(3-4):149-62. PMID: 14686788
The Forkhead Box (Fox) proteins are an extensive family of transcription factors that shares homology in the winged helix DNA binding domain. Liver regeneration studies with the -3 kb transthyretin...
38.
Krupczak-Hollis K, Wang X, Dennewitz M, Costa R
Hepatology . 2003 Dec; 38(6):1552-62. PMID: 14647066
The Forkhead Box (Fox) proteins are an extensive family of transcription factors that shares homology in the winged helix DNA-binding domain and the members of which play essential roles in...
39.
Costa R, Kalinichenko V, Holterman A, Wang X
Hepatology . 2003 Dec; 38(6):1331-47. PMID: 14647040
No abstract available.
40.
Kalinichenko V, Gusarova G, Kim I, Shin B, Yoder H, Clark J, et al.
Am J Physiol Lung Cell Mol Physiol . 2003 Nov; 286(3):L521-30. PMID: 14607778
The forkhead box (Fox) f1 transcription factor is expressed in the mouse splanchnic (visceral) mesoderm, which contributes to development of the liver, gallbladder, lung, and intestinal tract. Pulmonary hemorrhage and...