Robert H Blelloch
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Explore the profile of Robert H Blelloch including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
428
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Recent Articles
1.
High-throughput, Efficient, and Unbiased Capture of Small RNAs from Low-input Samples for Sequencing
Belair C, Hu T, Chu B, Freimer J, Cooperberg M, Blelloch R
Sci Rep
. 2019 Feb;
9(1):2262.
PMID: 30783180
MicroRNAs hold great promise as biomarkers of disease. However, there are few efficient and robust methods for measuring microRNAs from low input samples. Here, we develop a high-throughput sequencing protocol...
2.
Tran N, Kissner M, Subramanyam D, Parchem R, Laird D, Blelloch R
Stem Cells
. 2016 Apr;
34(7):1985-91.
PMID: 27066911
The embryonic stem cell cycle (ESCC) and let-7 families of miRNAs function antagonistically in the switch between mouse embryonic stem cell self-renewal and somatic differentiation. Here, we report that the...
3.
Shenoy A, Danial M, Blelloch R
EMBO J
. 2015 Feb;
34(9):1180-94.
PMID: 25715649
The molecular basis of astrocyte differentiation and maturation is poorly understood. As microRNAs have important roles in cell fate transitions, we set out to study their function during the glial...
4.
Shenoy A, Blelloch R
Nat Rev Mol Cell Biol
. 2014 Aug;
15(9):565-76.
PMID: 25118717
microRNAs (miRNAs) are important modulators of development. Owing to their ability to simultaneously silence hundreds of target genes, they have key roles in large-scale transcriptomic changes that occur during cell...
5.
Krishnakumar R, Blelloch R
Curr Opin Genet Dev
. 2013 Aug;
23(5):548-55.
PMID: 23948105
Cells are constantly changing their state of equilibrium in response to internal and external stimuli. These changes in cell identity are driven by highly coordinated modulation of gene expression. This...
6.
Song G, Sharma A, Roll G, Ng R, Lee A, Blelloch R, et al.
Hepatology
. 2010 May;
51(5):1735-43.
PMID: 20432256
Unlabelled: MicroRNAs (miRNAs) constitute a new class of regulators of gene expression. Among other actions, miRNAs have been shown to control cell proliferation in development and cancer. However, whether miRNAs...
7.
Blelloch R, Hochedlinger K, Yamada Y, Brennan C, Kim M, Mintz B, et al.
Proc Natl Acad Sci U S A
. 2004 Aug;
101(39):13985-90.
PMID: 15306687
Embryonal carcinoma (EC) cells have served as a model to study the relationship between cancer and cellular differentiation given their potential to produce tumors and, to varying degrees, participate in...