Robert G Lloyd
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Explore the profile of Robert G Lloyd including associated specialties, affiliations and a list of published articles.
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1964
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Recent Articles
11.
Rudolph C, Mahdi A, Upton A, Lloyd R
Genetics
. 2010 Jul;
186(2):473-92.
PMID: 20647503
Replication of the Escherichia coli chromosome usually initiates at a single origin (oriC) under control of DnaA. Two forks are established and move away in opposite directions. Replication is completed...
12.
Briggs G, Yu J, Mahdi A, Lloyd R
Nucleic Acids Res
. 2010 Jun;
38(19):6433-46.
PMID: 20525790
The DNA-binding protein RdgC has been identified as an inhibitor of RecA-mediated homologous recombination in Escherichia coli. In Neisseria species, RdgC also has a role in virulence-associated antigenic variation. We...
13.
Zhang J, Mahdi A, Briggs G, Lloyd R
Genetics
. 2010 Feb;
185(1):23-37.
PMID: 20157002
RuvABC and RecG are thought to provide alternative pathways for the late stages of recombination in Escherichia coli. Inactivation of both blocks the recovery of recombinants in genetic crosses. RuvABC...
14.
Rudolph C, Upton A, Briggs G, Lloyd R
DNA Repair (Amst)
. 2010 Jan;
9(3):210-23.
PMID: 20093100
The RecG protein of Escherichia coli is a double-stranded DNA translocase that unwinds a variety of branched DNAs in vitro, including Holliday junctions, replication forks, D-loops and R-loops. Coupled with...
15.
Guy C, Atkinson J, Gupta M, Mahdi A, Gwynn E, Rudolph C, et al.
Mol Cell
. 2009 Nov;
36(4):654-66.
PMID: 19941825
Nucleoprotein complexes present challenges to genome stability by acting as potent blocks to replication. One attractive model of how such conflicts are resolved is direct targeting of blocked forks by...
16.
Grove J, Wood S, Briggs G, Oldham N, Lloyd R
DNA Repair (Amst)
. 2009 Oct;
8(12):1434-43.
PMID: 19846353
RecN is a highly conserved, SMC-like protein in bacteria. It plays an important role in the repair of DNA double-strand breaks and is therefore a key factor in maintaining genome...
17.
Rudolph C, Upton A, Lloyd R
Mol Microbiol
. 2009 Oct;
74(4):940-55.
PMID: 19818016
Duplication and transmission of chromosomes require precise control of chromosome replication and segregation. Here we present evidence that RecG is a major factor influencing these processes in bacteria. We show...
18.
Rudolph C, Upton A, Harris L, Lloyd R
Mol Microbiol
. 2009 Jun;
73(3):352-66.
PMID: 19538444
Little is known about what happens when forks meet to complete DNA replication in any organism. In this study we present data suggesting that the collision of replication forks is...
19.
Rudolph C, Upton A, Lloyd R
DNA Repair (Amst)
. 2008 Jul;
7(9):1589-602.
PMID: 18644471
In dividing cells, the stalling of replication fork complexes by impediments to DNA unwinding or by template imperfections that block synthesis by the polymerase subunits is a serious threat to...
20.
Grove J, Harris L, Buckman C, Lloyd R
DNA Repair (Amst)
. 2008 Jul;
7(9):1517-30.
PMID: 18606573
DNA double-strand breaks threaten the stability of the genome, and yet are induced deliberately during meiosis in order to provoke homologous recombination and generate the crossovers needed to promote faithful...