Robert C Rostomily
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Explore the profile of Robert C Rostomily including associated specialties, affiliations and a list of published articles.
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57
Citations
1792
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Recent Articles
1.
Upadhyay S, Lee M, Zhang L, Oany A, Mikheeva S, Mikheev A, et al.
Mol Pharmacol
. 2025 Mar;
107(2):100009.
PMID: 40023516
1,1-Bis(3'-indolyl)-1-(3,5-disubstitutedphenyl)methane (DIM-3,5) compounds are dual receptor ligands that bind both orphan nuclear receptor 4A1 (NR4A1) and NR4A2. Knockdown of NR4A1 or NR4A2 by RNA interference in glioblastoma (GBM) cells decreased...
2.
Bomsztyk K, Mar D, Denisenko O, Powell S, Vishnoi M, Yin Z, et al.
Lab Invest
. 2024 Oct;
104(12):102160.
PMID: 39426568
Precision oncology is driven by biomarkers. For glioblastoma multiforme (GBM), the most common malignant adult primary brain tumor, O-methylguanine-DNA methyltransferase (MGMT) gene promoter methylation is an important prognostic and treatment...
3.
Maloji Rao V, Vasquez V, Kodavati M, Mitra J, Provasek V, Voh A, et al.
Res Sq
. 2024 Aug;
PMID: 39108479
Intracerebral hemorrhage (ICH) poses acute fatality and long-term neurological risks due to hemin and iron accumulation from hemoglobin breakdown. Our observation that hemin induces DNA double-strand breaks (DSBs), prompting a...
4.
Cruz-Garza J, Bhenderu L, Taghlabi K, Frazee K, Guerrero J, Hogan M, et al.
Commun Biol
. 2024 Jul;
7(1):869.
PMID: 39020197
Electrokinetic convection-enhanced delivery (ECED) utilizes an external electric field to drive the delivery of molecules and bioactive substances to local regions of the brain through electroosmosis and electrophoresis, without the...
5.
Vishnoi M, Dereli Z, Yin Z, Kong E, Kinali M, Thapa K, et al.
Res Sq
. 2024 Jul;
PMID: 38947019
Background: Interactions among tumor, immune, and vascular niches play major roles in driving glioblastoma (GBM) malignancy and treatment responses. The composition, heterogeneity, and localization of extracellular core matrix proteins (CMPs)...
6.
Vishnoi M, Dereli Z, Yin Z, Kong E, Kinali M, Thapa K, et al.
Res Sq
. 2023 Oct;
PMID: 37790408
Interactions among tumor, immune and vascular niches play major roles in driving glioblastoma (GBM) malignancy and treatment responses. The composition, heterogeneity, and localization of extracellular core matrix proteins (CMPs) that...
7.
Mikheeva S, Funk C, Horner P, Rostomily R, Mikheev A
Mol Oncol
. 2023 Jul;
18(3):517-527.
PMID: 37507199
TWIST1 (TW) is a pro-oncogenic basic helix-loop-helix (bHLH) transcription factor and promotes the hallmark features of malignancy (e.g., cell invasion, cancer cell stemness, and treatment resistance), which contribute to poor...
8.
Vishnoi M, Dereli Z, Yin Z, Kong E, Kinali M, Thapa K, et al.
bioRxiv
. 2023 Jun;
PMID: 37333072
Interactions among tumor, immune and vascular niches play major roles in driving glioblastoma (GBM) malignancy and treatment responses. The composition, heterogeneity, and localization of extracellular core matrix proteins (CMPs) that...
9.
Cruz-Garza J, Taghlabi K, Bhenderu L, Gupta S, Pandey A, Frazier A, et al.
J Vis Exp
. 2023 Apr;
(193).
PMID: 37067267
The overall goal of this procedure is to perform stereotaxy in the pig brain with real-time magnetic resonance (MR) visualization guidance to provide precise infusions. The subject was positioned prone...
10.
Patterson J, Farach A, Singh M, Britz G, Rostomily R
J Neurosurg Case Lessons
. 2023 Jan;
5(5).
PMID: 36718868
Background: Leptomeningeal carcinomatosis is a rare feature of metastasis that is characterized by thickening and increased contrast enhancement throughout the meninges of the central nervous system (CNS). Leptomeningeal disease (LMD)...