Robert C Robbins
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Explore the profile of Robert C Robbins including associated specialties, affiliations and a list of published articles.
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7719
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Recent Articles
11.
Sedehi D, Finocchiaro G, Tibayan Y, Chi J, Pavlovic A, Kim Y, et al.
J Cardiol
. 2014 Sep;
66(1):57-62.
PMID: 25238885
Background: Surgical myectomy and alcohol septal ablation (ASA) aim to decrease left ventricular outflow tract (LVOT) gradient in hypertrophic cardiomyopathy (HCM). Outcome of myectomy beyond 10 years has rarely been...
12.
Stubbendorff M, Hua X, Deuse T, Ali Z, Reichenspurner H, Maegdefessel L, et al.
J Vis Exp
. 2014 Jun;
(87).
PMID: 24893977
Various in vivo laboratory rodent models for the induction of artery stenosis have been established to mimic diseases that include arterial plaque formation and stenosis, as observed for example in...
13.
Schaffer J, Singh S, Joyce D, Reitz B, Robbins R, Zamanian R, et al.
Circulation
. 2014 Apr;
129(16):e458.
PMID: 24753555
No abstract available.
14.
Deuse T, Hua X, Wang D, Maegdefessel L, Heeren J, Scheja L, et al.
Nature
. 2014 Apr;
509(7502):641-4.
PMID: 24747400
Despite the introduction of antiproliferative drug-eluting stents, coronary heart disease remains the leading cause of death in the United States. In-stent restenosis and bypass graft failure are characterized by excessive...
15.
Khatri P, Roedder S, Kimura N, De Vusser K, Morgan A, Gong Y, et al.
J Exp Med
. 2013 Oct;
210(11):2205-21.
PMID: 24127489
Using meta-analysis of eight independent transplant datasets (236 graft biopsy samples) from four organs, we identified a common rejection module (CRM) consisting of 11 genes that were significantly overexpressed in...
16.
Lijkwan M, Hellingman A, Bos E, Van der Bogt K, Huang M, Kooreman N, et al.
Hum Gene Ther
. 2013 Oct;
25(1):41-9.
PMID: 24090375
In this study, we target the hypoxia inducible factor-1 alpha (HIF-1-alpha) pathway by short hairpin RNA interference therapy targeting prolyl hydroxylase-2 (shPHD2). We use the minicircle (MC) vector technology as...
17.
Huber B, Ransohoff J, Ransohoff K, Riegler J, Ebert A, Kodo K, et al.
Stem Cells
. 2013 Sep;
31(11):2354-63.
PMID: 24038578
Rationale: Human embryonic stem cell (hESC) derivatives are attractive candidates for therapeutic use. The engraftment and survival of hESC derivatives as xenografts or allografts require effective immunosuppression to prevent immune...
18.
Navarrete E, Liang P, Lan F, Sanchez-Freire V, Simmons C, Gong T, et al.
Circulation
. 2013 Sep;
128(11 Suppl 1):S3-13.
PMID: 24030418
Background: Drug-induced arrhythmia is one of the most common causes of drug development failure and withdrawal from market. This study tested whether human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) combined...
19.
Chen I, Paulmurugan R, Nielsen C, Wang D, Chow V, Robbins R, et al.
Mol Imaging Biol
. 2013 Aug;
16(2):224-34.
PMID: 23955099
Purpose: The efficacy and safety of cardiac gene therapy depend critically on the level and the distribution of therapeutic gene expression following vector administration. We aimed to develop a titratable...
20.
Chen I, Gheysens O, Li Z, Rasooly J, Wang Q, Paulmurugan R, et al.
Hum Gene Ther Methods
. 2013 Aug;
24(5):279-88.
PMID: 23937265
Hypoxia-inducible factor-1 alpha (HIF-1α) gene therapy holds great promise for the treatment of myocardial ischemia. Both preclinical and clinical evaluations of this therapy are underway and can benefit from a...