Robert Baertsch
Overview
Explore the profile of Robert Baertsch including associated specialties, affiliations and a list of published articles.
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30
Citations
12402
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Recent Articles
1.
Nickols N, Nazarian R, Zhao S, Tan V, Uzunangelov V, Xia Z, et al.
Prostate Cancer Prostatic Dis
. 2019 Feb;
22(4):531-538.
PMID: 30804427
Background: Metastatic castration resistant prostate cancer (mCRPC) is incurable and progression after drugs that target the androgen receptor-signaling axis is inevitable. Thus, there is an urgent need to develop more...
2.
Sweetnam C, Mocellin S, Krauthammer M, Knopf N, Baertsch R, Shrager J
BMC Bioinformatics
. 2018 Sep;
19(1):341.
PMID: 30257653
Background: We describe a prototype implementation of a platform that could underlie a Precision Oncology Rapid Learning system. Results: We describe the prototype platform, and examine some important issues and...
3.
Newton Y, Novak A, Swatloski T, McColl D, Chopra S, Graim K, et al.
Cancer Res
. 2017 Nov;
77(21):e111-e114.
PMID: 29092953
Vast amounts of molecular data are being collected on tumor samples, which provide unique opportunities for discovering trends within and between cancer subtypes. Such cross-cancer analyses require computational methods that...
4.
Doronina L, Churakov G, Kuritzin A, Shi J, Baertsch R, Clawson H, et al.
Genome Res
. 2017 Mar;
27(6):997-1003.
PMID: 28298429
Rapid species radiation due to adaptive changes or occupation of new ecospaces challenges our understanding of ancestral speciation and the relationships of modern species. At the molecular level, rapid radiation...
5.
Schmitz J, Noll A, Raabe C, Churakov G, Voss R, Kiefmann M, et al.
Nat Commun
. 2016 Oct;
7:12997.
PMID: 27708261
Tarsiers are phylogenetically located between the most basal strepsirrhines and the most derived anthropoid primates. While they share morphological features with both groups, they also possess uncommon primate characteristics, rendering...
6.
Lee J, Phillips J, Smith B, Park J, Stoyanova T, McCaffrey E, et al.
Cancer Cell
. 2016 Apr;
29(4):536-547.
PMID: 27050099
MYCN amplification and overexpression are common in neuroendocrine prostate cancer (NEPC). However, the impact of aberrant N-Myc expression in prostate tumorigenesis and the cellular origin of NEPC have not been...
7.
Sokolov A, Carlin D, Paull E, Baertsch R, Stuart J
PLoS Comput Biol
. 2016 Mar;
12(3):e1004790.
PMID: 26960204
We present a novel regularization scheme called The Generalized Elastic Net (GELnet) that incorporates gene pathway information into feature selection. The proposed formulation is applicable to a wide variety of...
8.
Smith B, Sokolov A, Uzunangelov V, Baertsch R, Newton Y, Graim K, et al.
Proc Natl Acad Sci U S A
. 2015 Oct;
112(47):E6544-52.
PMID: 26460041
Evidence from numerous cancers suggests that increased aggressiveness is accompanied by up-regulation of signaling pathways and acquisition of properties common to stem cells. It is unclear if different subtypes of...
9.
Doronina L, Churakov G, Shi J, Brosius J, Baertsch R, Clawson H, et al.
Mol Biol Evol
. 2015 Sep;
32(12):3194-204.
PMID: 26337548
Freed from the competition of large raptors, Paleocene carnivores could expand their newly acquired habitats in search of prey. Such changing conditions might have led to their successful distribution and...
10.
Farrell C, OLeary N, Harte R, Loveland J, Wilming L, Wallin C, et al.
Nucleic Acids Res
. 2013 Nov;
42(Database issue):D865-72.
PMID: 24217909
The Consensus Coding Sequence (CCDS) project (http://www.ncbi.nlm.nih.gov/CCDS/) is a collaborative effort to maintain a dataset of protein-coding regions that are identically annotated on the human and mouse reference genome assemblies...