Robert B Petersen
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Explore the profile of Robert B Petersen including associated specialties, affiliations and a list of published articles.
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95
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2313
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Recent Articles
11.
Ma L, Li X, Liu C, Yan W, Ma J, Petersen R, et al.
Curr Pharm Des
. 2022 Sep;
28(37):3033-3048.
PMID: 36111767
Parkinson's disease (PD) is a common neurodegenerative disease that affects the motor system and progressively worsens with age. Current treatment options for PD mainly target symptoms, due to our limited...
12.
Wang S, Zheng J, Ma L, Petersen R, Xu L, Huang K
Biochim Biophys Acta Gen Subj
. 2021 Nov;
1866(2):130061.
PMID: 34822925
Protein aggregation is correlated with the onset and progression of protein misfolding diseases (PMDs). Inhibiting the generation of toxic aggregates of misfolded proteins has been proposed as a therapeutic approach...
13.
Yang J, Song Q, Niu S, Chen H, Petersen R, Zhang Y, et al.
J Cell Physiol
. 2021 Jul;
237(1):98-117.
PMID: 34289108
Angiopoietin-like proteins (ANGPTLs), a family of eight secreted glycoproteins termed ANGTPL1-8, are involved in angiogenesis, lipid metabolism, cancer progression, and inflammation. Their roles in regulating lipid metabolism have been intensively...
14.
Yuan Y, Liu C, Chen X, Sun Y, Xiong M, Fan Y, et al.
Mol Nutr Food Res
. 2021 Jun;
65(16):e2100417.
PMID: 34129274
Scope: DNA methylation contributes to obesity, but the role of the DNA demethylase ten-eleven translocation protein 1 (Tet1) in obesity remains unclear. Vitamin C is a cofactor for the Tet...
15.
Wang J, Xiao Y, Liu C, Huang Y, Petersen R, Zheng L, et al.
Arch Biochem Biophys
. 2021 Jan;
700:108768.
PMID: 33485848
Numerous neurological and non-neurological disorders are associated with dysfunction of epigenetic modulators, and methyl CpG binding protein 2 (MeCP2) is one of such proteins. Initially identified as a transcriptional repressor,...
16.
Zhang W, Yang D, Yuan Y, Liu C, Chen H, Zhang Y, et al.
Diabetes
. 2020 Sep;
69(12):2642-2654.
PMID: 32994276
Cross talk among different tissues and organs is a hotspot in metabolic research. Recent studies have revealed the regulatory roles of a number of myokines in metabolism. Here, we report...
17.
Quan C, Chen Y, Wang X, Yang D, Wang Q, Huang Y, et al.
Cancer Lett
. 2020 Sep;
495:41-52.
PMID: 32920200
Tyrosine kinase inhibitor (TKI) treatment is the first-line therapy for non-small cell lung cancer (NSCLC) caused by activating mutations of epidermal growth factor receptor (EGFR). However, acquired resistance to EGFR-TKI...
18.
Shen P, Dang J, Wang Z, Zhang W, Yuan J, Lang Y, et al.
Mol Neurobiol
. 2020 Sep;
58(1):21-33.
PMID: 32889654
Alteration in cellular prion protein (PrP) localization on the cell surface through mediation of the glycosylphosphatidylinositol (GPI) anchor has been reported to dramatically affect the formation and infectivity of its...
19.
Li Y, Yang C, Wang S, Yang D, Zhang Y, Xu L, et al.
Int J Biol Macromol
. 2020 Jul;
163:562-573.
PMID: 32629061
Protein fibrils drive the onset and progression of many diseases in a prion-like manner, i.e. they transcellular propagate through the extracellular space to health cells to initiate toxic aggregation as...
20.
Sun Y, Wang Q, Zhang Y, Geng M, Wei Y, Liu Y, et al.
J Hepatol
. 2020 Jun;
73(3):603-615.
PMID: 32593682
Background & Aims: Obesity is an independent risk factor for malignancies, including hepatocellular carcinoma (HCC). However, it remains unknown whether maternal obesity affects the incidence of HCC in offspring. Thus,...