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Robert B Petersen

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Articles 95
Citations 2313
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Recent Articles
1.
Stadler J, Garmo L, Doyle D, Cheng C, Richardson G, Waheed Z, et al.
Front Cell Dev Biol . 2025 Jan; 12():1467417. PMID: 39834388
Introduction: Ischemic stroke is a devastating neurovascular condition that occurs when cerebral tissue fails to receive an adequate supply of oxygen. Despite being a leading cause of death and disability...
2.
Yu L, Li X, Shi T, Li N, Zhang D, Liu X, et al.
Int J Biol Macromol . 2025 Jan; 297:139875. PMID: 39818366
Parkinson's disease (PD), a neurodegenerative disorder without cure, is characterized by the pathological aggregation of α-synuclein (α-Syn) in Lewy bodies. Classic deposition pathway and condensation pathway contribute to α-Syn aggregation,...
3.
Yang J, Wan S, Song Q, Xie Y, Wan J, Zhou Y, et al.
Cell Death Differ . 2024 Nov; PMID: 39592710
Upon genotoxic stresses, cells employ various DNA damage responses (DDRs), including DNA damage repair or apoptosis, to safeguard genome integrity. However, the determinants among different DDRs choices are largely unknown....
4.
Li X, Yu L, Liu X, Shi T, Zhang Y, Xiao Y, et al.
Nat Commun . 2024 Oct; 15(1):8748. PMID: 39384788
Parkinson's disease (PD) and Dementia with Lewy Bodies (DLB) are neurodegenerative disorders characterized by the accumulation of α-synuclein aggregates. α-synuclein forms droplets via liquid-liquid phase separation (LLPS), followed by liquid-solid...
5.
Fan Y, Yuan Y, Xiong M, Jin M, Zhang D, Yang D, et al.
Theranostics . 2023 Nov; 13(15):5348-5364. PMID: 37908721
Increased methylation of key genes has been observed in kidney diseases, suggesting that the ten-eleven translocation (Tet) methyl-cytosine dioxygenase family as well as 5mC oxidation may play important roles. As...
6.
Yang C, Xu H, Yang D, Xie Y, Xiong M, Fan Y, et al.
Nat Commun . 2023 Jul; 14(1):4261. PMID: 37460623
Acute kidney injury (AKI) exhibits high morbidity and mortality. Kidney injury molecule-1 (KIM1) is dramatically upregulated in renal tubules upon injury, and acts as a biomarker for various renal diseases....
7.
Xiong M, Chen H, Fan Y, Jin M, Yang D, Chen Y, et al.
Theranostics . 2023 Jun; 13(10):3387-3401. PMID: 37351176
Ischemia-reperfusion injury (I/R) is a common cause of acute kidney injury (AKI). Post-ischemic recovery of renal blood supply plays an important role in attenuating injury. Exogenous application of elabela (ELA)...
8.
Petersen R, Walter B
Front Aging Neurosci . 2023 Jun; 15:1193197. PMID: 37266403
No abstract available.
9.
Yang D, Fan Y, Xiong M, Chen Y, Zhou Y, Liu X, et al.
EMBO Rep . 2023 Apr; 24(6):e56128. PMID: 37042626
Surgery-induced renal ischemia and reperfusion (I/R) injury and nephrotoxic drugs like cisplatin can cause acute kidney injury (AKI), for which there is no effective therapy. Lipid accumulation is evident following...
10.
Ma L, Li X, Petersen R, Peng A, Huang K
Biophys Chem . 2023 Mar; 296:106984. PMID: 36889133
Protein misfolding diseases (PMDs) in humans are characterized by the deposition of protein aggregates in tissues, including Alzheimer's disease, Parkinson's disease, type 2 diabetes, and amyotrophic lateral sclerosis. Misfolding and...