Robert B Chadwick
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Explore the profile of Robert B Chadwick including associated specialties, affiliations and a list of published articles.
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11
Citations
421
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Recent Articles
1.
Esmailpour T, Riazifar H, Liu L, Donkervoort S, Huang V, Madaan S, et al.
J Med Genet
. 2014 Jan;
51(3):185-96.
PMID: 24431331
Introduction: Lenz microphthalmia syndrome (LMS) is a genetically heterogeneous X-linked disorder characterised by microphthalmia/anophthalmia, skeletal abnormalities, genitourinary malformations, and anomalies of the digits, ears, and teeth. Intellectual disability and seizure...
2.
Govoni K, Wergedal J, Chadwick R, Srivastava A, Mohan S
Am J Physiol Endocrinol Metab
. 2008 Sep;
295(5):E1172-80.
PMID: 18812464
It is generally well accepted that the pubertal surge in estrogen is responsible for the rapid bone accretion that occurs during puberty and that this effect is mediated by an...
3.
Srivastava A, Qin X, Wedhas N, Arnush M, Linkhart T, Chadwick R, et al.
J Biol Chem
. 2007 Sep;
282(48):35113-24.
PMID: 17897957
We have investigated the effect of tumor necrosis factor-alpha (TNF-alpha) on the production of extracellular matrix-degrading proteases in skeletal muscles. Using microarray, quantitative PCR, Western blotting, and zymography, we found...
4.
Chadwick R, Bu L, Yu H, Hu Y, Wergedal J, Mohan S, et al.
Wound Repair Regen
. 2007 Mar;
15(2):275-84.
PMID: 17352761
MRL/Mpj mice are the only known strain of mouse that can regenerate cardiac lesions and completely heal ear punches without scarring. This study was undertaken to determine if MRL mice...
5.
Govoni K, Lee S, Chadwick R, Yu H, Kasukawa Y, Baylink D, et al.
Am J Physiol Endocrinol Metab
. 2006 Feb;
291(1):E128-36.
PMID: 16464905
Growth hormone (GH) is important in the development and maintenance of bone; however, the IGF-dependent and -independent molecular pathways involved remain to be established. We used microarray analysis to evaluate...
6.
Rundle C, Wang H, Yu H, Chadwick R, Davis E, Wergedal J, et al.
Bone
. 2005 Dec;
38(4):521-9.
PMID: 16321582
Microarray analysis of gene expression was performed in the healing femur fractures of 13-week-old male rats during the inflammatory stage of repair, at 3 days post-fracture, and the endochondral bone...
7.
Xing W, Baylink D, Kesavan C, Hu Y, Kapoor S, Chadwick R, et al.
J Cell Biochem
. 2005 Sep;
96(5):1049-60.
PMID: 16149068
To identify the genes and signal pathways responsible for mechanical loading-induced bone formation, we evaluated differential gene expression on a global basis in the tibias of C57BL/6J (B6) mice after...
8.
Mohan S, Kapoor A, Singgih A, Zhang Z, Taylor T, Yu H, et al.
J Bone Miner Res
. 2005 Aug;
20(9):1597-610.
PMID: 16059632
Unlabelled: Using a mouse mutant that fractures spontaneously and dies at a very young age, we identified that a deletion of the GULO gene, which is involved in the synthesis...
9.
Rae J, Scheys J, Clark K, Chadwick R, Kiefer M, Lippman M
Breast Cancer Res Treat
. 2004 Sep;
87(1):87-95.
PMID: 15377854
EGFRvIII is a constitutively activated truncated variant of the epidermal growth factor receptor (EGFR) which has been shown to increase tumorgenicity. There are conflicting reports on the extent of EGFRvIII...
10.
Jurevic R, Bai M, Chadwick R, White T, Dale B
J Clin Microbiol
. 2003 Jan;
41(1):90-6.
PMID: 12517831
beta-Defensins are cationic antimicrobial peptides expressed in epithelia. They exhibit antibacterial, antifungal, and antiviral properties. Defensins are a component of the innate immune response, and it has been proposed that...