Robert A B Keates
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Explore the profile of Robert A B Keates including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
195
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Recent Articles
1.
Islam S, Fieldhouse R, Anderson E, Taylor V, Keates R, Ford R, et al.
Mol Microbiol
. 2012 May;
84(6):1165-76.
PMID: 22554073
Heteropolymeric B-band O-antigen (O-Ag) biosynthesis in Pseudomonas aeruginosa PAO1 follows the Wzy-dependent pathway, beginning with translocation of undecaprenyl pyrophosphate-linked anionic O-Ag subunits (O units) from the inner to the outer...
2.
Chaulk S, Smith Frieday M, Arthur D, Culham D, Edwards R, Soo P, et al.
Biochemistry
. 2011 Mar;
50(15):3095-106.
PMID: 21381725
Transporter ProP mediates osmolyte accumulation in Escherichia coli cells exposed to high osmolality media. The cytoplasmic ProQ protein amplifies ProP activity by an unknown mechanism. The N- and C-terminal domains...
3.
Keates R, Culham D, Vernikovska Y, Zuiani A, Boggs J, Wood J
Biochemistry
. 2010 Sep;
49(41):8847-56.
PMID: 20828170
Osmoregulatory transporters stimulate bacterial growth by mediating osmoprotectant uptake in response to increasing osmotic pressure. The ProP protein of Escherichia coli transports proline and other osmoprotectants. Like LacY, ProP is...
4.
McGuire A, Keates R, Cook S, Mangroo D
Biochem Cell Biol
. 2009 Apr;
87(2):431-43.
PMID: 19370060
Utp8p is an essential 80 kDa intranuclear tRNA chaperone that transports tRNAs from the nucleolus to the nuclear tRNA export receptors in Saccharomyces cerevisiae. To help understand the mechanism of...
5.
Culham D, Vernikovska Y, Tschowri N, Keates R, Wood J, Boggs J
Biochemistry
. 2008 Dec;
47(51):13584-93.
PMID: 19049385
ProP is an osmosensory transporter. The activities of ProP and ProP*, a cysteine-less, His(6)-tagged ProP variant, increase with osmotic pressure in cells and proteoliposomes. In proteoliposomes, ProP activity is osmolality-dependent...
6.
Tsatskis Y, Kwok S, Becker E, Gill C, Smith M, Keates R, et al.
Biochemistry
. 2007 Dec;
47(1):60-72.
PMID: 18076193
Protein ProP acts as an osmosensory transporter in diverse bacteria. C-Terminal residues 468-497 of Escherichia coli ProP (ProPEc) form a four-heptad homodimeric alpha-helical coiled coil. Arg 488, at a core...
7.
Parr C, Keates R, Bryksa B, Ogawa M, Yada R
Yeast
. 2007 Apr;
24(6):467-80.
PMID: 17447722
Saccharomyces cerevisiae proteinase A (saccharopepsin; EC 3.4.23.25) is a member of the aspartic proteinase superfamily (InterPro IPR001969), which are proteolytic enzymes distributed among a variety of organisms. Targeted to the...
8.
Liu F, Culham D, Vernikovska Y, Keates R, Boggs J, Wood J
Biochemistry
. 2007 Apr;
46(19):5647-55.
PMID: 17441691
Escherichia coli transporter ProP acts as both an osmosensor and an osmoregulator. As medium osmolality rises, ProP is activated and mediates H+-coupled uptake of osmolytes like proline. A homology model...
9.
Wenzel C, Daniels C, Keates R, Brewer D, Lam J
Mol Microbiol
. 2005 Aug;
57(5):1288-303.
PMID: 16102001
Di-N-acetylated uronic acid residues are unique sugar moieties observed in the lipopolysaccharides (LPS) of respiratory pathogens including several serotypes of Pseudomonas aeruginosa and several species of Bordetella. WbpD of P....
10.
Wood J, Culham D, Hillar A, Vernikovska Y, Liu F, Boggs J, et al.
Biochemistry
. 2005 Apr;
44(15):5634-46.
PMID: 15823022
Transporter ProP of Escherichia coli, a member of the major facilitator superfamily (MFS), acts as an osmosensor and an osmoregulator in cells and after purification and reconstitution in proteoliposomes. H(+)-osmoprotectant...