Riya Raghupathy
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Explore the profile of Riya Raghupathy including associated specialties, affiliations and a list of published articles.
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7
Citations
434
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Recent Articles
1.
Saewu A, Kongmanas K, Raghupathy R, Netherton J, Kadunganattil S, Linton J, et al.
Endocrinology
. 2019 Nov;
161(1).
PMID: 31730175
Cultures of Sertoli cells isolated from 20-day-old mice are widely used in research as substitutes for adult Sertoli cell cultures. This practice is based on the fact that Sertoli cells...
2.
Saewu A, Kadunganattil S, Raghupathy R, Kongmanas K, Diaz-Astudillo P, Hermo L, et al.
Reproduction
. 2017 Oct;
154(6):867-880.
PMID: 28971894
Clusterin (CLU) is known as an extracellular chaperone for proteins under stress, thus preventing them from aggregation and precipitation. We showed herein that CLU, expressed by principal cells of the...
3.
Dauner K, Eid W, Raghupathy R, Presley J, Zha X
J Biol Chem
. 2017 Feb;
292(14):5737-5747.
PMID: 28196862
The plasma membrane of mammalian cells undergoes constitutive endocytosis, endocytic sorting, and recycling, which delivers nutrients to the lysosomes. The receptors, along with membrane lipids, are normally returned to the...
4.
Raghupathy R, Anilkumar A, Polley A, Pal Singh P, Yadav M, Johnson C, et al.
Cell
. 2015 Apr;
161(3):581-594.
PMID: 25910209
Understanding how functional lipid domains in live cell membranes are generated has posed a challenge. Here, we show that transbilayer interactions are necessary for the generation of cholesterol-dependent nanoclusters of...
5.
Saha S, Raghupathy R, Mayor S
Methods Mol Biol
. 2014 Nov;
1251:151-73.
PMID: 25391799
Several models have been proposed to understand the structure and organization of the plasma membrane in living cells. Predicated on equilibrium thermodynamic principles, the fluid-mosaic model of Singer and Nicholson...
6.
Yadav M, Raghupathy R, Saikam V, Dara S, Pal Singh P, Sawant S, et al.
Org Biomol Chem
. 2014 Jan;
12(7):1163-72.
PMID: 24413835
Synthesis of first generation non-hydrolysable C-phosphonate GPI analogs, viz., 6-O-(2-amino-2-deoxy-α-d-glucopyranosyl)-d-myo-inositol-1-O-(sn-3,4-bis(palmitoyloxy)butyl-1-phosphonate) and 6-O-(2-amino-2-deoxy-α-d-glucopyranosyl)-d-myo-inositol-1-O-(sn-2,3-bis(palmitoyloxy)propyl-1-phosphonate) 23b, is reported. The target compounds were synthesized by the coupling of α-pseudodisaccharide 21 with phosphonic acids 18a...
7.
Goswami D, Gowrishankar K, Bilgrami S, Ghosh S, Raghupathy R, Chadda R, et al.
Cell
. 2008 Dec;
135(6):1085-97.
PMID: 19070578
Several cell-surface lipid-tethered proteins exhibit a concentration-independent, cholesterol-sensitive organization of nanoscale clusters and monomers. To understand the mechanism of formation of these clusters, we investigate the spatial distribution and steady-state...