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Rivkah Gonsky

Explore the profile of Rivkah Gonsky including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 347
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Recent Articles
1.
Shih T, Yusung S, Gonsky R, Dutra-Clarke R, Ziring D, Rabizadeh S, et al.
Inflamm Bowel Dis . 2022 Dec; 29(2):328-331. PMID: 36508344
No abstract available.
2.
Biener-Ramanujan E, Rosier F, Coetzee S, McGovern D, Hazelett D, Targan S, et al.
Front Immunol . 2022 Dec; 13:999155. PMID: 36466822
Ribonuclease T2 gene (RNASET2) variants are associated in genome wide association studies (GWAS) with risk for several autoimmune diseases, including Crohn's disease (CD). In T cells, a functional and biological...
3.
Jacob N, Kumagai K, Abraham J, Shimodaira Y, Ye Y, Luu J, et al.
Sci Rep . 2020 Oct; 10(1):18189. PMID: 33097818
Tumor necrosis factor-like cytokine 1A (TL1A, TNFSF15) is implicated in inflammatory bowel disease, modulating the location and severity of inflammation and fibrosis. TL1A expression is increased in inflamed mucosa and...
4.
Gonsky R, Fleshner P, Deem R, Biener-Ramanujan E, Li D, Potdar A, et al.
Gastroenterology . 2017 Apr; 153(1):219-232. PMID: 28400196
Background & Aims: Variants in the tumor necrosis factor superfamily member 15 gene (TNFSF15, also called TL1A) have been associated with risk for inflammatory bowel disease (IBD). TL1A affects expression...
5.
Gonsky R, Deem R, Landers C, Haritunians T, Yang S, Targan S
Inflamm Bowel Dis . 2014 Aug; 20(10):1794-801. PMID: 25171510
Background: Mucosal expression of interferon (IFN)-γ plays a pivotal role in the pathogenesis of inflammatory bowel disease (IBD) and IBD risk regions flank IFNG. The conserved IFNG rs1861494 T/C introduces...
6.
Gonsky R, Deem R, Targan S
Cytokine . 2013 May; 63(1):36-42. PMID: 23642711
TL1A/TNFSF15 has been associated with IBD (inflammatory bowel disease) in GWAS (genome-wide association study) and plays a role mediating mucosal inflammation in IBD. Higher TL1A expression is associated with disease...
7.
Shih D, Michelsen K, Barrett R, Biener-Ramanujan E, Gonsky R, Zhang X, et al.
Adv Exp Med Biol . 2010 Dec; 691:279-88. PMID: 21153332
No abstract available.
8.
Gonsky R, Deem R, Landers C, Derkowski C, Berel D, McGovern D, et al.
Inflamm Bowel Dis . 2010 Sep; 17(1):171-8. PMID: 20848535
Background: High antibody reactivity toward microbial antigens in Crohn's disease (CD) patients is predictive of a more aggressive disease course. However, few ulcerative colitis (UC) patients exhibit serologic reactivity toward...
9.
Biener-Ramanujan E, Gonsky R, Ko B, Targan S
FEBS Lett . 2010 Apr; 584(11):2376-80. PMID: 20403353
TL1A, a TNF member implicated in autoimmune diseases, is a transmembrane protein that is processed to release soluble TL1A (TL1A-S). TL1A-S induces a Th1 response, although the functional significance of...
10.
Shih D, Kwan L, Chavez V, Cohavy O, Gonsky R, Chang E, et al.
Eur J Immunol . 2009 Oct; 39(11):3239-50. PMID: 19839006
TL1A is a member of the TNF superfamily and its expression is increased in the mucosa of inflammatory bowel disease patients. Neutralizing anti-mouse TL1A Ab attenuates chronic colitis in two...