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Rita Silva-Gomes

Explore the profile of Rita Silva-Gomes including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 205
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Recent Articles
1.
Silva-Gomes R, Caldeira I, Fernandes R, Cunha C, Carvalho A
J Leukoc Biol . 2024 Mar; 116(3):469-486. PMID: 38498599
Fungal infections present a significant global public health concern, impacting over 1 billion individuals worldwide and resulting in more than 3 million deaths annually. Despite considerable progress in recent years,...
2.
Porte R, Silva-Gomes R, Theroude C, Parente R, Asgari F, Sironi M, et al.
Elife . 2023 May; 12. PMID: 37222419
is a major pathogen in children, elderly subjects, and immunodeficient patients. Pentraxin 3 (PTX3) is a fluid-phase pattern recognition molecule (PRM) involved in resistance to selected microbial agents and in...
3.
Davoudian S, Piovani D, Desai A, Mapelli S, Leone R, Sironi M, et al.
Front Immunol . 2022 Oct; 13:979232. PMID: 36189302
Background: Early prognostic stratification of patients with sepsis is a difficult clinical challenge. Aim of this study was to evaluate novel molecules in association with clinical parameters as predictors of...
4.
Silva-Gomes R, Mapelli S, Boutet M, Mattiola I, Sironi M, Grizzi F, et al.
J Leukoc Biol . 2021 Aug; 111(4):817-836. PMID: 34346525
The MS4A gene family encodes 18 tetraspanin-like proteins, most of which with unknown function. MS4A1 (CD20), MS4A2 (FcεRIβ), MS4A3 (HTm4), and MS4A4A play important roles in immunity, whereas expression and...
5.
Fraga A, Trigo G, Murthy R, Akhtar S, Hebbur M, Pacheco A, et al.
PLoS Negl Trop Dis . 2019 Aug; 13(8):e0007113. PMID: 31425525
Buruli Ulcer (BU) is a cutaneous disease caused by Mycobacterium ulcerans. The pathogenesis of this disease is closely related to the secretion of the toxin mycolactone that induces extensive destruction...
6.
Mattiola I, Tomay F, De Pizzol M, Silva-Gomes R, Savino B, Gulic T, et al.
Nat Immunol . 2019 Jul; 20(8):1012-1022. PMID: 31263276
The plasma membrane tetraspan molecule MS4A4A is selectively expressed by macrophage-lineage cells, but its function is unknown. Here we report that MS4A4A was restricted to murine and human mononuclear phagocytes...
7.
Silva J, Goncalves C, Costa C, Sousa J, Silva-Gomes R, Castro A, et al.
J Control Release . 2016 Jun; 235:112-124. PMID: 27261333
Tuberculosis (TB), a disease caused by the human pathogen Mycobacterium tuberculosis, recently joined HIV/AIDS on the top rank of deadliest infectious diseases. Low patient compliance due to the expensive, long-lasting...
8.
Capela C, Dossou A, Silva-Gomes R, Sopoh G, Makoutode M, Menino J, et al.
PLoS Negl Trop Dis . 2016 Apr; 10(4):e0004671. PMID: 27128681
Introduction: Buruli ulcer (BU) is a severe necrotizing human skin disease caused by Mycobacterium ulcerans. Clinically, presentation is a sum of these diverse pathogenic hits subjected to critical immune-regulatory mechanisms....
9.
Silva-Gomes R, Marcq E, Trigo G, Goncalves C, Longatto-Filho A, Castro A, et al.
PLoS Negl Trop Dis . 2015 Dec; 9(12):e0004265. PMID: 26625302
Buruli Ulcer (BU) is a necrotizing skin disease caused by Mycobacterium ulcerans infection. BU is characterized by a wide range of clinical forms, including non-ulcerative cutaneous lesions that can evolve...
10.
Capela C, Sopoh G, Houezo J, Fiodessihoue R, Dossou A, Costa P, et al.
PLoS Negl Trop Dis . 2015 Sep; 9(9):e0004005. PMID: 26355838
Buruli Ulcer (BU) is a neglected infectious disease caused by Mycobacterium ulcerans that is responsible for severe necrotizing cutaneous lesions that may be associated with bone involvement. Clinical presentations of...