Rita Mukhopadhyay
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Explore the profile of Rita Mukhopadhyay including associated specialties, affiliations and a list of published articles.
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32
Citations
1179
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Recent Articles
1.
Ojha C, Rodriguez M, Dever S, Mukhopadhyay R, El-Hage N
J Biomed Sci
. 2016 Oct;
23(1):74.
PMID: 27784307
MicroRNAs (miRNAs), which are small non-coding RNAs expressed by almost all metazoans, have key roles in the regulation of cell differentiation, organism development and gene expression. Thousands of miRNAs regulating...
2.
Sharma M, Mandal G, Mandal S, Bhattacharjee H, Mukhopadhyay R
Mol Biochem Parasitol
. 2015 Aug;
201(2):139-45.
PMID: 26259900
Leishmania major aquaglyceroporin (AQP1) is an adventitious metalloid channel that allows the bidirectional movement of arsenite and antimonite. Here we demonstrate that AQP1 is subjected to proteasome-dependent degradation. Treatment of...
3.
Plourde M, Ubeda J, Mandal G, Lima do Monte-Neto R, Mukhopadhyay R, Ouellette M
Mol Biochem Parasitol
. 2015 Jul;
201(2):108-11.
PMID: 26222914
The Leishmania aquaglyceroporin AQP1 plays an important physiological role in water and uncharged polar solutes transport, volume regulation, osmotaxis, and is a key determinant of antimony resistance. By targeted gene...
4.
Mandal G, Mandal S, Sharma M, Santos Charret K, Papadopoulou B, Bhattacharjee H, et al.
PLoS Negl Trop Dis
. 2015 Feb;
9(2):e0003500.
PMID: 25714343
Leishmania is a digenetic protozoan parasite causing leishmaniasis in humans. The different clinical forms of leishmaniasis are caused by more than twenty species of Leishmania that are transmitted by nearly...
5.
Mukhopadhyay R, Bhattacharjee H, Rosen B
Biochim Biophys Acta
. 2013 Dec;
1840(5):1583-91.
PMID: 24291688
Background: Aquaporins (AQPs), members of a superfamily of transmembrane channel proteins, are ubiquitous in all domains of life. They fall into a number of branches that can be functionally categorized...
6.
Uzcategui N, Figarella K, Bassarak B, Meza N, Mukhopadhyay R, Ramirez J, et al.
Cell Physiol Biochem
. 2013 Nov;
32(4):880-8.
PMID: 24217645
Background: Trypanosoma brucei is a primitive parasitic protozoan that thrives in diverse environments such as the midgut of the tsetse fly and the blood of a mammalian host. For an...
7.
Mukherjee A, Boisvert S, Lima do Monte-Neto R, Coelho A, Raymond F, Mukhopadhyay R, et al.
Mol Microbiol
. 2013 Feb;
88(1):189-202.
PMID: 23421749
Antimonials are still the mainstay of treatment against leishmaniasis but drug resistance is increasing. We carried out short read next-generation sequencing (NGS) and comparative genomic hybridization (CGH) of three independent...
8.
Mandal G, Sharma M, Kruse M, Sander-Juelch C, Munro L, Wang Y, et al.
Mol Microbiol
. 2012 Jul;
85(6):1204-18.
PMID: 22779703
Leishmania major aquaglyceroporin (LmjAQP1) adventitiously facilitates the uptake of antimonite [Sb(III)], an active form of Pentostam® or Glucantime®, which are the first line of defence against all forms of leishmaniasis....
9.
Mukhopadhyay R, Mandal G, Atluri V, Figarella K, Uzcategui N, Zhou Y, et al.
Mol Biochem Parasitol
. 2010 Oct;
175(1):83-90.
PMID: 20888371
Leishmania major aquaglyceroporin LmAQP1 allows adventitious passage of antimonite, an activated form of the drug Pentostam, which is used as the first line treatment for leishmaniasis. The extracellular C-loop of...
10.
Mukhopadhyay R, Beitz E
Adv Exp Med Biol
. 2010 Jul;
679:57-69.
PMID: 20666224
Metalloids can severely harm human physiology in a toxicological sense if taken up from the environment in acute high doses or chronically. However, arsenic or antimony containing drugs are still...