Rina Plattner
Overview
Explore the profile of Rina Plattner including associated specialties, affiliations and a list of published articles.
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22
Citations
580
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0
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Recent Articles
1.
Lyon A, Tripathi R, Meeks C, He D, Wu Y, Liu J, et al.
Cancers (Basel)
. 2023 Feb;
15(3).
PMID: 36765910
Melanomas harboring mutations are a particularly aggressive and deadly subtype. If patients cannot tolerate or the melanomas are insensitive to immune checkpoint blockade, there are no effective 2nd-line treatment options....
2.
Daniels H, Knicely B, Miller A, Thompson A, Plattner R, Goellner E
Front Genet
. 2022 Nov;
13:940073.
PMID: 36338985
The DNA mismatch repair (MMR) pathway and its regulation are critical for genomic stability. Mismatch repair (MMR) follows replication and repairs misincorporated bases and small insertions or deletions that are...
3.
Hill K, McDowell A, McCorkle J, Schuler E, Ellingson S, Plattner R, et al.
Cancers (Basel)
. 2021 Apr;
13(8).
PMID: 33920029
Artesunate is the most common treatment for malaria throughout the world. Artesunate has anticancer activity likely through the induction of reactive oxygen species, the same mechanism of action utilized in...
4.
Tripathi R, Liu Z, Jain A, Lyon A, Meeks C, Richards D, et al.
Nat Commun
. 2020 Oct;
11(1):5463.
PMID: 33122628
Metastatic melanoma remains an incurable disease for many patients due to the limited success of targeted and immunotherapies. BRAF and MEK inhibitors reduce metastatic burden for patients with melanomas harboring...
5.
Tripathi R, Liu Z, Plattner R
Curr Pharmacol Rep
. 2019 Feb;
4(5):367-379.
PMID: 30746323
Purpose Of Review: The goal of this review is to summarize our current knowledge regarding how ABL family kinases are activated in solid tumors and impact on solid tumor development/progression,...
6.
He C, Plattner R, Rangnekar V, Zhou B, Liu C, Stewart R, et al.
Cancer Causes Control
. 2018 Nov;
30(1):41-51.
PMID: 30488343
Background: We evaluated five key proteins involved in various cancer-related pathways and assessed their relation to breast cancer recurrence. Methods: We used the Kentucky Cancer Registry to retrospectively identify primary...
7.
Tripathi R, Plattner R
Mol Cell Oncol
. 2018 Sep;
5(4):e1458016.
PMID: 30250913
Metastatic melanoma remains incurable for many due to its aggressive nature. Secreted cathepsins promote metastasis by cleaving matrix and activating pro-invasive proteases. We reported that ABL kinases induce cathepsin secretion...
8.
Tripathi R, Fiore L, Richards D, Yang Y, Liu J, Wang C, et al.
Sci Signal
. 2018 Feb;
11(518).
PMID: 29463776
The incidence of melanoma is increasing, particularly in young women, and the disease remains incurable for many because of its aggressive, metastatic nature and its high rate of resistance to...
9.
Baldwin L, Hoff J, Lefringhouse J, Zhang M, Jia C, Liu Z, et al.
Oncotarget
. 2014 Oct;
5(23):12203-17.
PMID: 25356755
Human ovarian cancer is diagnosed in the late, metastatic stages but the underlying mechanisms remain poorly understood. We report a surprising functional link between CD151-α3β1 integrin complexes and the malignancy...
10.
Fiore L, Ganguly S, Sledziona J, Cibull M, Wang C, Richards D, et al.
Oncogene
. 2013 Oct;
33(36):4508-4520.
PMID: 24096484
Metastasis suppressors comprise a growing class of genes whose downregulation triggers metastatic progression. In contrast to tumor suppressors, metastasis suppressors are rarely mutated or deleted, and little is known regarding...