Rika Tsuchida
Overview
Explore the profile of Rika Tsuchida including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
605
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Kato M, Maeda K, Nakahara R, Hirose H, Kondo A, Aki S, et al.
PNAS Nexus
. 2023 Oct;
2(10):pgad306.
PMID: 37822765
An acidic tumor microenvironment plays a critical role in tumor progression. However, understanding of metabolic reprogramming of tumors in response to acidic extracellular pH has remained elusive. Using comprehensive metabolomic...
2.
Nakahara R, Aki S, Sugaya M, Hirose H, Kato M, Maeda K, et al.
EMBO J
. 2023 Oct;
42(22):e114032.
PMID: 37781951
Bone marrow-derived cells (BMDCs) infiltrate hypoxic tumors at a pre-angiogenic state and differentiate into mature macrophages, thereby inducing pro-tumorigenic immunity. A critical factor regulating this differentiation is activation of SREBP2-a...
3.
Osawa T, Shimamura T, Saito K, Hasegawa Y, Ishii N, Nishida M, et al.
Cell Rep
. 2019 Oct;
29(1):89-103.e7.
PMID: 31577958
Tolerance to severe tumor microenvironments, including hypoxia and nutrient starvation, is a common feature of aggressive cancer cells and can be targeted. However, metabolic alterations that support cancer cells upon...
4.
Takagi M, Yoshida M, Nemoto Y, Tamaichi H, Tsuchida R, Seki M, et al.
J Natl Cancer Inst
. 2017 Oct;
109(11).
PMID: 29059438
Background: Neuroblastoma (NB) is the most common solid tumor found in children, and deletions within the 11q region are observed in 11% to 48% of these tumors. Notably, such tumors...
5.
Osawa T, Tsuchida R, Muramatsu M, Shimamura T, Wang F, Suehiro J, et al.
Cancer Res
. 2013 Mar;
73(10):3019-28.
PMID: 23492365
Antiangiogenic strategies can be effective for cancer therapy, but like all therapies resistance poses a major clinical challenge. Hypoxia and nutrient starvation select for aggressive qualities that may render tumors...
6.
Das B, Bayat-Mokhtari R, Tsui M, Lotfi S, Tsuchida R, Felsher D, et al.
Stem Cells
. 2012 Jun;
30(8):1685-95.
PMID: 22689594
Human embryonic stem cells (hESCs) have been reported to exert cytoprotective activity in the area of tissue injury. However, hypoxia/oxidative stress prevailing in the area of injury could activate p53,...
7.
Osawa T, Muramatsu M, Wang F, Tsuchida R, Kodama T, Minami T, et al.
Proc Natl Acad Sci U S A
. 2011 Dec;
108(51):20725-9.
PMID: 22143793
Histone demethylase JHDM1D (also known as KDM7A) modifies the level of methylation in histone and participates in epigenetic gene regulation; however, the role of JHDM1D in tumor progression is unknown....
8.
Wang F, Osawa T, Tsuchida R, Yuasa Y, Shibuya M
Cancer Sci
. 2011 Aug;
102(11):2007-13.
PMID: 21848913
By behaving as molecular hubs, scaffold proteins can assemble a large number of signaling molecules and organize complicated intracellular signaling networks in time and space. Owing to their crucial role...
9.
Wang F, Yamauchi M, Muramatsu M, Osawa T, Tsuchida R, Shibuya M
J Biol Chem
. 2011 Jan;
286(11):9097-106.
PMID: 21212275
Vascular endothelial growth factor (VEGF) is vital to physiological as well as pathological angiogenesis, and regulates a variety of cellular functions, largely by activating its 2 receptors, fms-like tyrosine kinase...
10.
Das B, Antoon R, Tsuchida R, Lotfi S, Morozova O, Farhat W, et al.
Neoplasia
. 2008 Sep;
10(10):1105-19.
PMID: 18813359
Squalene, an isoprenoid antioxidant is a potential cytoprotective agent against chemotherapy-induced toxicity. We have previously published that squalene protects light-density bone marrow cells against cis-diamminedichloroplatinum( II) (cisplatin)-induced toxicity without protecting...