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Rie L Rathje

Explore the profile of Rie L Rathje including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Sau S, Madsen A, Podbevsek P, Andersen N, Kumar T, Andersen S, et al.
J Org Chem . 2013 Sep; 78(19):9560-70. PMID: 24032477
The development of synthetic agents that recognize double-stranded DNA (dsDNA) is a long-standing goal that is inspired by the promise for tools that detect, regulate, and modify genes. Progress has...
2.
Karmakar S, Anderson B, Rathje R, Andersen S, Jensen T, Nielsen P, et al.
J Org Chem . 2011 Aug; 76(17):7119-31. PMID: 21827174
N2'-Pyrene-functionalized 2'-amino-α-L-LNAs (locked nucleic acids) display extraordinary affinity toward complementary DNA targets due to favorable preorganization of the pyrene moieties for hybridization-induced intercalation. Unfortunately, the synthesis of these monomers is...