Richard Y Ebright
Overview
Explore the profile of Richard Y Ebright including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
1347
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Fox D, Ebright R, Hong X, Russell H, Guo H, LaSalle T, et al.
NPJ Precis Oncol
. 2023 Mar;
7(1):25.
PMID: 36864091
Immune checkpoint blockade (ICB) has demonstrated efficacy in patients with melanoma, but many exhibit poor responses. Using single cell RNA sequencing of melanoma patient-derived circulating tumor cells (CTCs) and functional...
2.
Rajurkar M, Parikh A, Solovyov A, You E, Kulkarni A, Chu C, et al.
Cancer Discov
. 2022 Mar;
12(6):1462-1481.
PMID: 35320348
Significance: Colorectal cancers express abundant repeat elements that have a viral-like life cycle that can be therapeutically targeted with nucleoside reverse transcriptase inhibitors (NRTI) commonly used for viral diseases. NRTIs...
3.
Guo H, Golczer G, Wittner B, Langenbucher A, Zachariah M, Dubash T, et al.
Mol Cell
. 2021 Oct;
81(19):4041-4058.e15.
PMID: 34624217
Deregulation of oncogenic signals in cancer triggers replication stress. Immediate early genes (IEGs) are rapidly and transiently expressed following stressful signals, contributing to an integrated response. Here, we find that...
4.
Micalizzi D, Ebright R, Haber D, Maheswaran S
Cancer Res
. 2021 Jan;
81(3):517-524.
PMID: 33479028
Deregulation of the mRNA translational process has been observed during tumorigenesis. However, recent findings have shown that deregulation of translation also contributes specifically to cancer cell spread. During metastasis, cancer...
5.
Ebright R, Zachariah M, Micalizzi D, Wittner B, Niederhoffer K, Nieman L, et al.
Nat Commun
. 2020 Dec;
11(1):6311.
PMID: 33298946
Blood-borne metastasis to the brain is a major complication of breast cancer, but cellular pathways that enable cancer cells to selectively grow in the brain microenvironment are poorly understood. We...
6.
Ebright R, Lee S, Wittner B, Niederhoffer K, Nicholson B, Bardia A, et al.
Science
. 2020 Feb;
367(6485):1468-1473.
PMID: 32029688
Circulating tumor cells (CTCs) are shed into the bloodstream from primary tumors, but only a small subset of these cells generates metastases. We conducted an in vivo genome-wide CRISPR activation...
7.
Ligorio M, Sil S, Malagon-Lopez J, Nieman L, Misale S, Di Pilato M, et al.
Cell
. 2019 Jun;
178(1):160-175.e27.
PMID: 31155233
Single-cell technologies have described heterogeneity across tissues, but the spatial distribution and forces that drive single-cell phenotypes have not been well defined. Combining single-cell RNA and protein analytics in studying...
8.
Lin W, Das K, Degen D, Mazumder A, Duchi D, Wang D, et al.
Mol Cell
. 2018 Apr;
70(1):60-71.e15.
PMID: 29606590
Fidaxomicin is an antibacterial drug in clinical use for treatment of Clostridium difficile diarrhea. The active ingredient of fidaxomicin, lipiarmycin A3 (Lpm), functions by inhibiting bacterial RNA polymerase (RNAP). Here...
9.
Manier S, Huynh D, Shen Y, Zhou J, Yusufzai T, Salem K, et al.
Sci Transl Med
. 2017 May;
9(389).
PMID: 28490664
Multiple myeloma (MM) is a frequently incurable hematological cancer in which overactivity of MYC plays a central role, notably through up-regulation of ribosome biogenesis and translation. To better understand the...
10.
Vincent Jordan N, Bardia A, Wittner B, Benes C, Ligorio M, Zheng Y, et al.
Nature
. 2016 Aug;
537(7618):102-106.
PMID: 27556950
Circulating tumour cells in women with advanced oestrogen-receptor (ER)-positive/human epidermal growth factor receptor 2 (HER2)-negative breast cancer acquire a HER2-positive subpopulation after multiple courses of therapy. In contrast to HER2-amplified...