Richard W Padgett
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Explore the profile of Richard W Padgett including associated specialties, affiliations and a list of published articles.
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30
Citations
1355
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Recent Articles
1.
Lakdawala M, Madhu B, Faure L, Vora M, Padgett R, Gumienny T
Mol Biol Cell
. 2019 Nov;
30(26):3151-3160.
PMID: 31693440
Bone morphogenetic protein (BMP) signaling pathways control many developmental and homeostatic processes, including cell size and extracellular matrix remodeling. An understanding of how this pathway itself is controlled remains incomplete....
2.
Lin J, Vora M, Kane N, Gleason R, Padgett R
PLoS One
. 2019 May;
14(5):e0216628.
PMID: 31071172
The transforming growth factor-β (TGFβ) family plays an important role in many developmental processes and when mutated often contributes to various diseases. Marfan syndrome is a genetic disease with an...
3.
Savage-Dunn C, Gleason R, Liu J, Padgett R
Methods Mol Biol
. 2018 Nov;
1891:51-73.
PMID: 30414126
C. elegans has played a central role in the elucidation of the TGFβ pathway over the last two decades. This is due to the high conservation of the pathway components...
4.
Kane N, Vora M, Padgett R, Li Y
Fly (Austin)
. 2018 Jul;
12(2):105-117.
PMID: 30015555
Decapentaplegic (Dpp), the Drosophila homolog of the vertebrate bone morphogenetic protein (BMP2/4), is crucial for patterning and growth in many developmental contexts. The Dpp pathway is regulated at many different...
5.
Gleason R, Vora M, Li Y, Kane N, Liao K, Padgett R
PLoS One
. 2017 Jul;
12(7):e0180681.
PMID: 28704415
Signal transduction of the conserved transforming growth factor-β (TGFβ) family signaling pathway functions through two distinct serine/threonine transmembrane receptors, the type I and type II receptors. Endocytosis orchestrates the assembly...
6.
Savage-Dunn C, Padgett R
Cold Spring Harb Perspect Biol
. 2017 Jan;
9(6).
PMID: 28096268
Transforming growth factor β (TGF-β) and related ligands have potent effects on an enormous diversity of biological functions in all animals examined. Because of the strong conservation of TGF-β family...
7.
Kane N, Vora M, Varre K, Padgett R
G3 (Bethesda)
. 2016 Oct;
7(1):87-93.
PMID: 27793971
Genome editing using the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and associated nuclease (Cas9) enables specific genetic modifications, including deletions, insertions, and substitutions in numerous organisms, such as the...
8.
Akhurst R, Padgett R
Sci Signal
. 2015 Oct;
8(399):re10.
PMID: 26486175
The highly conserved wiring of the SMAD-dependent transforming growth factor β (TGFβ) superfamily signaling pathway has been mapped over the last 20 years after molecular discovery of its component parts....
9.
Gleason R, Akintobi A, Grant B, Padgett R
Proc Natl Acad Sci U S A
. 2014 Feb;
111(7):2578-83.
PMID: 24550286
The transforming growth factor β (TGFβ) superfamily of signaling pathways, including the bone morphogenetic protein (BMP) subfamily of ligands and receptors, controls a myriad of developmental processes across metazoan biology....
10.
Li Y, Padgett R
PLoS One
. 2012 Mar;
7(3):e32910.
PMID: 22412948
microRNAs (miRNAs) are small, conserved, non-coding RNAs that contribute to the control of many different cellular processes, including cell fate specification and growth control. Drosophila bantam, a conserved miRNA, is...